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Found 138 clinical trials
A Feasibility Study to Further the Development of Lung Cancer-based Precision Medicine

The purpose of this study is to further advancements in biospecimens (blood cellular free component, e.g., plasma, serum, tissue, urine), in order to develop precision medicine, for lung cancer

lung carcinoma
Accepts healthy volunteers
lung cancer
lung cancer screening
  • 24 Feb, 2022
  • 1 location
Patienthèque of Finisterian (South of Brittany) Children With Cystic Fibrosis in the Time of Precision Medicine (MUCOthèque)

The objective of this study is to evaluate the relevance of Porphyromonas as a biomarker predicting the risk of P. aeruginosa primocolonization in children form 0 to 18 years old with cystic fibrosis.

sweat test
diagnostic procedures
cftr gene
  • 04 Oct, 2022
  • 1 location
Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal Polyps

Asthma and chronic rhinosinusitis (CRS) are inflammatory diseases of the respiratory tract, asthma from the lower part, and CRS, from the upper part. In theory, these parts are correlated as if they are one single organ, namely "united airways", which means that if one is affected by any condition, the …

other disease
local anesthetic
  • 19 Nov, 2021
  • 1 location
Study Evaluating the Efficacy of a Double Immunotherapy Combined With Olaparib in Patients With Solid Cancers and Carriers of Homologous Recombination Repair Genes After Olaparib Treatment

The study propose to generate a clinical trial based on precision medicine to evaluate the use of immunotherapy in patients with altered homologous recombination repair genes and without

  • 31 May, 2021
  • 8 locations
Hypothesizing the Genesis of Infectious Diseases and Epidemics Through an Integrated (HYGIEIA)

-omics data. Identifying key determinants and mechanisms of biological variability responsible for phenotypic differences will lead to a better management of patients through the application of precision

Accepts healthy volunteers
  • 15 Oct, 2022
  • 1 location
INSPIRE Trial for Abdominal Infections

The INSPIRE Abdominal Infection Trial is a cluster-randomized controlled trial of HCA Healthcare hospitals comparing routine empiric antibiotic stewardship practices with real-time, precision

  • 07 Oct, 2022
  • 100 locations
Internet Based Cognitive Behavioral Therapy in Pediatric Chronic Pancreatitis

disability and enhance HRQOL; it will also identify genetic risk factors and clinical and behavioral phenotypic factors associated with treatment response to enable precision medicine approaches.

abdominal pain
  • 29 May, 2022
  • 1 location
Detection of Viable CTCs Using the EPIDROP Technology in Metastatic Prostate Cancer (EPIDROP)

The use of liquid biopsy could be the key for precision medicine. Circulating tumor cells (CTCs) are the most studied circulating biomarkers used to assess the metastatic process and they have

  • 09 Jun, 2021
  • 2 locations
Physiopathological Study of Genetic Modulation of Cardiovascular Effect of PPAR-Alpha Activation (MAGNETIC-PPARA) (MAGNETIC)

. If successful, this project will pave the way to a precision medicine approach to prescribe fenofibrate optimally, offering a cardio-protective drug to those patients that are most likely to

  • 10 Oct, 2022
  • 1 location
Metabotyping of Overweight and Obese Children (RecSAMP)

metabolomics a very powerful tool towards precision medicine. Yet, the excellence of stool in reflecting the intertwining thereof is completely unexplored for pediatric purposes, whereas blood sampling

Accepts healthy volunteers
  • 07 Oct, 2022
  • 7 locations