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Found 138 clinical trials
PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study

The primary objective of this study is to evaluate several interventions given to participants with severe asthma. Interventions are administered in a crossover manner with 16-week treatment periods followed by 8 to 16 week washout.

bronchodilator
corticosteroids
albuterol
methacholine
  • 194 views
  • 04 Oct, 2022
  • 28 locations
Heart Failure Precision Medicine Study

The study aims to test the hypothesis that multi-omics studies can identify Heart Failure profiles at risk of adverse outcomes and evaluate a telemonitoring intervention in the optimization of guideline-directed medical therapy.

heart failure
nesiritide
b-type natriuretic peptide
natriuretic peptide
medical therapy
  • 5 views
  • 24 Mar, 2022
  • 1 location
Community Health Workers and Precision Medicine

effectively improve knowledge and receipt of evidence-based precision medicine cancer care services among low-income and minority patients.

cancer diagnosis
cancer care
primary cancer
  • 0 views
  • 24 Mar, 2022
  • 1 location
Precision Medicine for Sng/Pain Control

precision medicine for sore /pain control via the genetic markers. Investigators will recruit 80 myofascial pain patients from Department of Physical Medicine and Rehabilitation, National Taiwan University

  • 0 views
  • 22 Dec, 2021
  • 1 location
PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy (PEACH)

A Phase I open-label, multicenter study, to evaluate the safety, feasibility, and maximum tolerated dose (MTD) of treating children with newly diagnosed DIPG or recurrent neuroblastoma with molecular targeted therapy in combination with adoptive cell therapy (Total tumor mRNA-pulsed autologous Dendritic Cells (DCs) (TTRNA-DCs), Tumor-specific ex vivo expanded autologous lymphocyte …

colony stimulating factor
granulocyte colony stimulating factor
filgrastim
cancer
bone marrow procedure
  • 0 views
  • 14 May, 2022
  • 2 locations
Immunoclassification of Psoriasis: a Strategy for Precision Medicine

Through the combination of clinical manifestations and omics, the investigators aim to explore the skin cell atlas in different stages of psoriasis lesions, establish a clinical classification standard for psoriasis, and guide the precise treatment of psoriasis.

Accepts healthy volunteers
  • 0 views
  • 10 Apr, 2023
  • 1 location
Targeting Cerebrovascular Reactivity for Precision Medicine: Pilot Trial of Atorvastatin

The purpose of this study is to evaluate the effect of atorvastatin on brain vessel reactivity and with it on blood flow in people with mild cognitive impairment.

Accepts healthy volunteers
  • 0 views
  • 22 Oct, 2022
  • 1 location
Prognostic Value of Precision Medicine in Patients With MINOCA (PROMISE Trial).

The aim of our study is to evaluate if the use of a precision-medicine approach with a specific therapy tailored on the underlying pathogenic mechanism will improve the quality-of-life in MINOCA

  • 0 views
  • 26 Nov, 2021
  • 3 locations
Systemic Neoadjuvant and Adjuvant Control by Precision Medicine in Rectal Cancer (SYNCOPE)

Rectal cancer represents the most complex area of multidisciplinary treatment in bowel surgery. In 2017, there were 1221 new rectal cancers in Finland. The prognosis of colorectal cancer (CRC) patients these days is almost exclusively driven by the occurrence of the metastatic form of the disease. The treatment of rectal …

  • 0 views
  • 22 Mar, 2022
  • 1 location
Novel Precision Medicine Approach to Treatment of Osteoporosis Based on Bone Turnover

Osteoporosis affects 24.5% of women over 65 and results in fracture-related hospital admissions exceeding those of heart attacks, strokes and breast cancer combined. Current treatment options do not account for differences between age-related and estrogen deficiency related osteoporosis, because of the need for bone biopsies for determination. This study will …

calcium
vitamin d
hypercalcemia
breast cancer
risedronate
  • 0 views
  • 25 May, 2022
  • 1 location