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Found 138 clinical trials
Targeting the Gut-brain Axis to Facilitate Weight Loss in High Fat Diet Consumers

The primary objective is to test if fat intake moderates the ability of Oleoylthanolamide (OEA) to improve weight loss maintenance after the LEARN weight loss program.

  • 12 Nov, 2021
  • 1 location
TranspulmonarY Estrogen Gradient and Estrogen Receptors (TYEGER) in PAH (TYEGER)

Pulmonary arterial hypertension (PAH) is a disease characterized by elevated pressures in the blood vessels of the lungs that is not caused by another disease processes. More specifically, it is defined by a mean pulmonary artery pressure > 25 mm Hg, a pulmonary vascular resistance > 3 Wood Units (WU), …

pulmonary arterial pressure
right heart catheterization
Accepts healthy volunteers
left ventricular end-diastolic pressure
  • 23 Mar, 2022
  • 1 location
Development of Non-Invasive Brain Stimulation Techniques

Background Noninvasive brain stimulation (NIBS) may help diagnose and treat psychiatric and neurological illness. But there is not enough research on how to apply NIBS. This includes how strong to make it, where on the brain to apply it, and for how long. Researchers also want to see what the …

Accepts healthy volunteers
  • 04 Oct, 2022
  • 1 location
PREcision Medicine in Cancer in Odense, Denmark (PRECODE)

The traditional approach to cancer treatment has changes from using drugs approved for the specific cancer diagnosis to a tumor agnostic approach when treating solid tumors. How often will tumor biopsy and genomic profiling in patients with advanced solid tumors with no further evidence based treatment options result in biomarker-driven …

  • 03 Jun, 2022
  • 1 location
Prediction of Recurrence and Complications of Nephrolithiasis Using a Precision Medicine Approach (PRECILITH)

Nephrolithiasis is a disease caused by the formation of kidney stones in the urinary tract which can then partially or completely obstruct the latter causing an extremely sharp pain called renal colic. In industrialized countries, it affects 10 to 20% of the population, and is the most common kidney disease.The …

  • 24 Mar, 2022
  • 1 location
Genome-based Management of Patients in Precision Medicine (Ge-Med) Towards a Genomic Health Program (GE-MED)

The GE-MED APPROACH project will enroll patients (n = appr. 12.000) with unclear molecular cause of the disease, suspected genetic cause of the disease without detailed molecular analysis like Whole Exome Sequencing (WES). The novelty of this study is to integrate genomic health concepts into immediate clinical care. To achieve …

  • 23 May, 2022
  • 1 location
Scalable Communication Modalities for Returning Genetic Research Results (BWHS RoR)

Efforts to examine the utility of alternate modalities for genetic results disclosure has widespread implications for how precision medicine research might yield direct health benefits for study

  • 08 Apr, 2023
The BEST Trial: Biomarkers for Evaluating Spine Treatments (BEST)

. The primary objective of this trial is to inform a precision medicine approach to the treatment of Chronic Low-Back Pain by estimating an algorithm for optimally assigning treatments based on an

  • 22 Oct, 2022
  • 10 locations
A Study to Examine the Clinical Value of Comprehensive Genomic Profiling Performed by Belgian NGS Laboratories: a Belgian Precision Study of the BSMO in Collaboration With the Cancer Centre

patients with advanced/metastatic solid tumours broader access to precision medicine To describe the landscape of genomic alterations and quantify the actionable variants detected by

breast cancer
  • 05 Oct, 2021
  • 12 locations
Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

The overarching objective of this study is to use novel precision medicine strategies based on inherited and acquired leukemia-specific genomic features and targeted treatment approaches to

flow cytometry
  • 07 Oct, 2022
  • 7 locations