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Found 140 clinical trials
Featured trial
Alzheimer's Disease and Precision Medicine Research Among Native People

This project intends to address the gaps in Alzheimer's disease (AD) and precision medicine (PM) research in American Indian and Alaska Native (AI/AN) populations by comparing written and

Accepts healthy volunteers
  • 02 Mar, 2023
  • 1 location
Featured trial
HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma

Gene transfer is a new cancer therapy takes white blood cells from a person and grows them in a lab. The cells are changed with a virus to attack tumor cells, then returned to the person. Researchers want to see if this therapy fights kidney cancer cells. Metastatic renal cell …

clear cell renal cell carcinoma
primary cancer
clear cell carcinoma
renal cell cancer
  • 22 Dec, 2020
  • 1 location
Evaluating a Novel Individualised Treatment Strategy for Carbapenem-Resistant Gram-Negative Bacteria Infections

Carbapenem-resistant (CR) Gram negative bacteria (GNB) - which are resistant to carbapenems (a last-line potent antibiotic with a high therapeutic index) - are also resistant to all other beta-lactam antibiotics. Most CRGNB are also extensively-drug resistant (XDR) (resistant to all classes of antibiotics except polymyxins and/or tigecycline) or pan-drug resistant …

  • 21 Feb, 2022
  • 1 location
PRIME Care (PRecision Medicine In MEntal Health Care) 2.0

Background: In the last several years, commercial pharmacogenetic (PGx) testing for the selection of psychotropic medications has become widespread as a means of implementing "precision medicine

  • 21 Jul, 2021
  • 1 location
Mindfulness-Oriented Recovery Enhancement (MORE) in Heroin Addiction

that can be used for enhancing precision medicine with the goal of reducing morbidity and mortality associated with opiate addiction.

  • 25 Jan, 2021
  • 1 location
Precision Guided Tacrolimus Dosing in Pediatric Heart Transplant

elimination of these agents. The goal of this research proposal is to clinically validate an innovative precision medicine strategy for dosing the immunosuppressant tacrolimus in pediatric heart transplant

  • 19 Jun, 2022
  • 2 locations
INSPIRE Trial for Skin and Soft Tissue Infections

, precision medicine computerized physician order entry (CPOE) smart prompts providing the probability that a non-critically ill adult admitted with skin and soft tissue infection is infected with a resistant

  • 07 Oct, 2022
  • 101 locations
Myeloma-Developing Regimens Using Genomics (MyDRUG) (MyDRUG)

The MyDRUG study is a type of Precision Medicine trial to treat patients with drugs targeted to affect specific genes that are mutated as part of the disease. Mutations in genes can lead to

  • 07 Feb, 2022
  • 13 locations
Prescision Medicine in Obstructive Sleep Apnea, Cardiovascular and Cerebrovascular Disease: AI Electrocardiogram Patch Does it All

Obstructive Sleep apnea(OSA) is a disease with multiple causes, and treatments are very diverse. Patients and doctors have a lot of choices. The concept of precision medicine is needed to

Accepts healthy volunteers
  • 23 Oct, 2022
  • 1 location
Aging and the Mitochondrial Response to Exercise Training, Measured by Noninvasive 31P Magnetic Resonance Spectroscopy (MoTrMito) (MoTrMito)

The goal of the study is to determine whether aerobic or resistant exercise can improve in vivo mitochondrial capacity of skeletal muscle cells similarly in healthy younger, middle aged and older adults. This confers long-term changes in this tissue which in-turn contribute to improved metabolic health and functional capacity through …

Accepts healthy volunteers
  • 16 Oct, 2022
  • 1 location