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Found 28 clinical trials
Double Simultaneous Uterotonic Agents Versus Single Agent Regimen to Prevent Early Postpartum Hemorrhage

To determine the effectiveness of using two medications simultaneously versus one medication, as is standard of care, in preventing early postpartum hemorrhage. There have been studies

Accepts healthy volunteers
  • 0 views
  • 26 Mar, 2022
  • 1 location
TRAnexamic Acid for Preventing Blood Loss Following a Cesarean Delivery in Women With Placenta pREVIA (TRAAPrevia)

Several randomized, controlled trials, mostly involving women undergoing cesarean delivery, have shown that the prophylactic intravenous administration of 1 g of tranexamic acid after childbirth reduced blood loss. Most were small, single-centre trials with considerable methodologic limitations. It is important to emphasize that none of these RCTs has included women …

placenta previa
tranexamic acid
cesarean section
  • 0 views
  • 24 Apr, 2022
  • 1 location
Iron Infusion Into a Vein Compared to Iron Tablet Taken by Mouth for Treating Iron Deficiency Anemia in Pregnancy (IVON) (IVON)

Background: Anaemia in pregnancy is a public health burden with high incidence in Africa. Currently high dose oral iron is recommended for treatment of mild to moderate anaemia and blood transfusion for severe anaemia. The high dose oral iron is often poorly tolerated and associated with several side effects. Various …

Accepts healthy volunteers
  • 4 views
  • 10 Jul, 2022
  • 10 locations
Video Debriefing at the Delivery Ward - Empowering Obstetric Teams to High Performance

Postpartum hemorrhage continues to be the leading cause of maternal morbidity and mortality worldwide. Successful management of postpartum hemorrhage requires not only administration of the

Accepts healthy volunteers
  • 0 views
  • 29 Oct, 2022
  • 1 location
The Prophylactic Role of Tranexamic Acid in High Risk Pregnant Women Undergoing Elective Cesarean Section in Prevention of Postpartum Hemorrhage

The aim of the study is to assess the prophylactic role of tranexamic acid in reducing blood loss during and after elective cesarean section delivery in high risk patients. Comparing effect of administration of 1gm of TXA half an hour before elective C-section , effect of administration of 1gm of …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
World Maternal Antifibrinolytic Trial_2 (WOMAN-2)

Postpartum haemorrhage (PPH) is responsible for about 100,000 maternal deaths every year, almost all of which occur in low and middle income countries. When given within three hours of birth

  • 0 views
  • 04 Oct, 2022
  • 23 locations
Prevent Postpartum Hemorrhage in Women With Von Willebrand Disease: The VWD-WOMAN Trial

®); or recombinant Von Willebrand factor (rVWF, Vonvendi®) alone to prevent postpartum hemorrhage after vaginal or caesarean delivery. The primary endpoint is quantitative blood loss (QBL) by a

bleeding tendency
fibrinogen
ristocetin
hysterectomy
vonvendi
  • 0 views
  • 04 Oct, 2022
  • 1 location
Use of Tranexamic Acid After Vaginal Delivery With Episiotomy a RCT Placebo Control Trail

The objective of this study is to assess the effect of TA treatment on decline in Hb levels following vaginal delivery with an episiotomy, compared to a control group not receiving TA.

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Quantifying the Impact of the Peanut Ball on the Duration of the Active Stage of Labor

Prolonged labor is associated with adverse maternal and fetal outcomes including infection, postpartum hemorrhage and increased NICU admission. One of the most common indications for cesarean

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 4 locations
Sofosbuvir/Velpatasvir Treatment of Chronic Hepatitis C During Pregnancy (STORC)

This is a multicenter, single arm study of Sofosbuvir/Velpatasvir (SOF/VEL) for treatment of chronic hepatitis C infection during pregnancy. Treatment will be initiated during the second or third trimester in approximately 100 pregnant people. Maternal participants will take one SOF/VEL tablet once daily for 12 weeks (84 days) and followed …

  • 0 views
  • 06 May, 2022
  • 1 location