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Found 53 clinical trials
TXA in Spine Surgery

transfusions, and postoperative blood loss following open spine surgery.

  • 27 Jan, 2021
  • 1 location
Single Versus Multi-Dose Oral and Intravenous Tranexamic Acid Patients at High Risk for Blood Transfusion After Spine Surgery

transfusions, and postoperative blood loss following open spine surgery. The regimen that utilizes multiple doses of oral TXA will significantly minimize post-operative blood loss and transfusion requirements

  • 23 Mar, 2022
  • 1 location
Chronic Subdural Hematoma and Aspirin (SECA)

The aim of this randomized, blinded, placebo controlled clinical study is to compare the peri- and postoperative bleeding and cardiovascular complication rates of patients undergoing burr-hole

  • 03 Mar, 2022
  • 1 location
Effect of Preoperative Carbohydrate Loading on Post-operative Insulin Resistance After Donor Hepatectomy.

It's a randomized control trial to compare the effect of preoperative carbohydrate loading versus fasting on post operative insulin resistance after donor hepatectomy in terms of donor outcomes. Investigator will analyze the data and elucidate the value of post operative insulin resistance in reducing the occurrence of complications, length of …

Accepts healthy volunteers
  • 07 Apr, 2022
  • 1 location
Dexamethasone and Postoperative Bleeding Following Tonsillectomy in Children

treatment in routine anaesthesia practice in such surgical setting. However, in the last decade, there have been arguments about the potential role of Dexamethasone in increasing the risk of postoperative

  • 06 Oct, 2021
  • 2 locations
DEPOSITION - Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery (DEPOSITION)

The aim is to conduct a double-dummy multi-centre randomized controlled clinical trial of application of topical dose of tranexamic acid (TxA) versus the usual intravenous TxA in patients undergoing on-pump cardiac surgery.

postoperative bleeding
postoperative hemorrhage
heart surgery
coronary artery bypass graft
tranexamic acid
  • 24 Apr, 2022
  • 6 locations
Preoperative Hexakapron Reduces Bleeding in Bariatric Surgery (PHORBBS)

Prophylactic use of tranexamic acid to reduce intra and postoperative bleeding in primary sleeve gastrectomy procedures will be studied.

  • 31 Jan, 2022
  • 1 location
A Comparison of the Resection Rate for Cold and Hot Snare Polypectomy for 5-15 mm Colorectal Polyps

snare polypectomy (CSP). Due to the use of electrocautery, HSP has been shown to cause damage to the deep submucosa, the muscularis propria and submucosal arteries, resulting in postoperative bleeding

Accepts healthy volunteers
  • 01 Mar, 2022
  • 1 location
The HeLiX (Hemorrhage During Liver Resection: traneXamic Acid) Trial (HeLiX)

This is a Phase III multicentre randomized controlled trial (RCT) to evaluate the impact of tranexamic acid (TXA) on perioperative blood transfusion in patients undergoing liver resection. The rationale for this study includes: (1) experimental evidence supporting the use of TXA in other surgical populations; (2) lack of evidence in …

liver surgery
blood transfusion
primary cancer
  • 23 Mar, 2022
  • 10 locations
Early Femoral Block in Elderly With Hip Fracture

Assess if the addition of an early femoral nerve block (performed within 2 hours from the admission in emergency department through a femoral nerve catheter) in the elderly patients (> 70 years) with hip fracture, reduces the incidence of postoperative delirium assessed by CAM 3Ds test, compared to the traditional …

femoral neck fracture
nerve block
  • 25 Feb, 2022
  • 1 location