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Found 19 clinical trials
Sequential Neo-adjuvant Chemotherapy Followed by Capecitabine Vs. Conventional Adjuvant Chemotherapy in Breast Cancer (NACVCAC)

This study evaluates whether sequential neo-adjuvant chemotherapy plus surgery followed by Capecitabine could achieve additional benefits over traditional postoperative chemotherapy. In the

cancer
renal function
capecitabine
breast cancer
carcinoma
  • 0 views
  • 25 Feb, 2022
  • 1 location
The Role of Postoperative Cycles in the Perioperative Chemotherapy for Gastric Cancer (STOPEROPCHEM)

EOX chemotherapy regimen. The patients will be randomized to the postoperative chemotherapy or to the follow-up arm.

endoscopy
capecitabine
laparoscopy
cancer chemotherapy
endoscopic ultrasound
  • 26 views
  • 22 Jan, 2022
  • 2 locations
Adjuvant CAPECITABINE in High Risk PSEUDOMYXOMA PERITONEI Patients (ACAPP)

This is a phase II, mono institutional, non comparative study, evaluating adjuvant capecitabine in patients affected by KRAS mutated Pseudomyxoma peritonei treated with cytoreductive surgery and HIPEC. Patient will be treated with 8 cycles of the study regimen that include: Capecitabine 1250 mg/m2 PO BID day 1-14 q21 days

  • 0 views
  • 27 Apr, 2022
  • 1 location
Neoadjuvant FOLFOXIRI Versus Immediate Surgery for Stage II and III Colon Cancers

surgery. The investigators conducted the present randomized study to explore whether perioperative chemotherapy with FOLFOXIRI regimen compared with postoperative chemotherapy could improve disease-free

  • 0 views
  • 23 Mar, 2022
  • 1 location
Evaluation of Tamoxifen's Efficacy for ER/PR Negative,ER-beta Positive Operable Breast Cancer Patients

receive tamoxifen (20 mg per day) or placebo (2# per day) within 6 weeks after postoperative chemotherapy and/or radiation therapy if needed (according to 2013 NCCN breast cancer guideline). If the breast

erbb2
mammogram
adjuvant therapy
herceptin
mastectomy
  • 30 views
  • 18 May, 2022
  • 17 locations
Study of Oral Metronidazole on Postoperative Chemotherapy in Colorectal Cancer

reduce the abundance of Fn in patients with high Fn, so as to explore whether oral metronidazole can improve the efficacy of postoperative chemotherapy in patients with colorectal cancer.

  • 0 views
  • 27 Jan, 2021
  • 4 locations
Efficacy of HIPEC in the Treatment of Advanced-Stage Epithelial Ovarian Cancer After Cytoreductive Surgery (EHTASEOCCS)

This project is a multi-center, prospective, randomized controlled clinical observation the safety and efficacy of hyperthermic intraperitoneal chemotherapy in the treatment of advanced-stage epithelial ovarian cancer after cytoreductive surgery. Median recurrence-free survival is the primary end points of this project.

ovarian epithelial carcinoma
cancer
peritoneal cancer
ovarian epithelial cancer
immunostimulant
  • 3 views
  • 17 Feb, 2022
  • 5 locations
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Locally Advanced Gastric Cancer

The efficacy of HIPEC in prevention of local recurrence, distant metastasis or peritoneal metastasis in locally advanced gastric cancer is not definite. The hypothesis of the trial is that radical gastrectomy combined with HIPEC is superior to only radical gastrectomy in terms of overall survival.

tegafur
gimeracil
metastasis
paclitaxel
cancer chemotherapy
  • 0 views
  • 04 Mar, 2022
  • 1 location
Neoadjuvant RCT Versus CT for Patients With Locally Advanced Potentially Resectable Adenocarcinoma of the GEJ

This is a multicenter, prospective, randomized, stratified, controlled, open-label study comparing neoadjuvant radiochemotherapy with FLOT versus FLOT chemotherapy alone fr patients with locally advanced, potentially resectable adenocarcinoma of the gastroesophageal junction (GEJ)

fluorouracil
calcium
flot
aptt
renal function
  • 0 views
  • 28 Sep, 2021
  • 1 location
Neoadjuvant Chemotherapy With Gemcitabine Plus Cisplatin Followed by Radical Liver Resection Versus Immediate Radical Liver Resection Alone With or Without Adjuvant Chemotherapy in Incidentally Detected Gallbladder Carcinoma After Simple Cholecystectomy or in Front of Radical Resection of BTC (GAIN)

Neoadjuvant chemotherapy with gemcitabine plus cisplatin followed by radical liver resection versus immediate radical liver resection alone with or without adjuvant chemotherapy in incidentally detected gallbladder carcinoma after simple cholecystectomy or in front of radical resection of BTC (ICC/ECC)

biliary tract cancer
cholangiocarcinoma
international normalized ratio
psychiatric disorder
cisplatin/gemcitabine
  • 4 views
  • 18 Feb, 2022
  • 1 location