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Found 21 clinical trials
Compression Hosiery to Avoid Post-Thrombotic Syndrome

Patients with a deep vein thrombosis (DVT) may develop long-term symptoms, e.g. lifelong leg pain, skin changes and occasionally ulceration, known as post-thrombotic syndrome (PTS). This affects

deep venous thrombosis of lower extremity
blood clot
clot
dvts
deep vein thrombosis
  • 0 views
  • 16 Sep, 2021
  • 12 locations
Statins for Venous Event Reduction in Patients With Venous Thromboembolism (SAVER)

The standard or usual treatment for patients diagnosed with deep vein thrombosis or pulmonary embolism is treatment with blood thinners (called anticoagulants). While treatment of blood clots with blood thinners is effective, some research has shown that adding a statin (medication used to lower cholesterol) may give extra protection. It …

rosuvastatin
blood clot
thromboembolism
statin
anticoagulants
  • 0 views
  • 13 Oct, 2022
  • 7 locations
REduced Dose Versus Full-dose of Direct Oral Anticoagulant After uNprOvoked Venous thromboEmbolism. (RENOVE)

Patients with unprovoked venous thromboembolism (VTE) or VTE associated with persistent risk factors have a high risk of recurrence after stopping anticoagulation. In these patients, international guidelines recommend indefinite anticoagulation. However, prolonged use of warfarin or DOAC at therapeutic dose is associated with a significant risk of bleeding. Consequently, it …

warfarin
rivaroxaban
anticoagulants
aspirin
apixaban
  • 7 views
  • 03 May, 2022
  • 26 locations
Tinzaparin Lead-In to Prevent the Post-Thrombotic Syndrome Phase IV Pilot Study (TILE)

Anticoagulants) to PTS (prevent post thrombotic syndrome) in patients with DVT (Deep Vein Thrombosis).

blood clot
tinzaparin
heparin
dvts
rivaroxaban
  • 0 views
  • 12 Oct, 2022
  • 4 locations
Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy - The C-TRACT Trial (C-TRACT)

The purpose of this study is to determine if the use of image-guided, endovascular therapy (EVT) is an effective strategy with which to reduce Post Thrombotic Syndrome (PTS) disease severity and

stenosis
blood clot
dvts
venous stasis
post thrombotic syndrome
  • 582 views
  • 21 Oct, 2022
  • 21 locations
Aspirin® Plus Rivaroxaban Versus Rivaroxaban Alone for the Prevention of Venous Stent Thrombosis in Patients With PTS (ARIVA)

suffering from post-thrombotic syndrome in the first 6 months following endovascular therapy To demonstrate tolerability of combination therapy of Aspirin® plus rivaroxaban in long-term treatment.

stenosis
blood clot
clot
duplex ultrasound
rivaroxaban
  • 55 views
  • 03 Jun, 2022
  • 6 locations
Mechanisms of Deep Vein Thrombosis (DVT) and Vein Wall Fibrosis

(Factor Xa inhibitors) in patients with lower extremity deep vein thrombosis (DVT). The efficacy of adjunctive treatments to prevent the development of post thrombotic syndrome (PTS) after DVT will be

  • 0 views
  • 22 Oct, 2021
  • 1 location
DEep VEin Lesion OPtimisation (DEVELOP) Trial (Develop)

rates of post-thrombotic syndrome. Follow up will be over a five-year period. This feasibility study is designed to include 60 patients. Should it be practicable a total of 594 patients would be

Accepts healthy volunteers
endovenous ablation
compression therapy
healing ulcer
  • 7 views
  • 28 Feb, 2022
  • 2 locations
Novel PET/CT and Treatment Strategies to Reduce PTS Following DVT

development of the post-thrombotic syndrome (PTS). New approaches are needed to improve the outcomes of patients with DVT, a disease that affects up to 600,000 patients per year in the US alone. DVT acutely

ulceration
deep venous thrombosis of lower extremity
blood clot
dvts
anticoagulants
  • 0 views
  • 28 Apr, 2022
Non-elastic Compression Garment Therapy Versus Control for Deep Vein Thrombosis: A Bayesian Adaptive Randomized Trial

The objective of the study is to conduct a Bayesian randomized trial comparing non-elastic compression garments applied with high pressure (Circaid group) with no compression (control group) in reducing signs and symptoms in the acute stage of DVT and subsequent postthrombotic syndrome. With a hypothesis that the Circaid group will …

acute deep venous thrombosis
leg swelling
deep venous thrombosis of lower extremity
dvts
post thrombotic syndrome
  • 12 views
  • 15 Oct, 2022
  • 6 locations