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Found 120 clinical trials
MRI in BPD Subjects

The investigators are wanting to learn more about early development of the lungs and to help them better understand prematurity and the development of a breathing disorder call BPD (Bronchopulmonary Dysplasia)

  • 23 Jan, 2021
  • 1 location
Sleep Apnea and Tromboembolic Disease

There is some evidence for a hypercoagulable state in sleep apnea-hipopnea syndrome (SAHS), which could play a role in the increased cardiovascular morbility and mortality. Respiratory alterations (hypoxia, hypoxia- reoxygenation) and sleep fragmentation that these patients suffer during the sleep may induce modifications in clotting-fibrinolisis factors that may be a …

sleep fragmentation
pulmonary embolism
obstructive sleep apnea
  • 07 Nov, 2020
  • 1 location
Could HRV be a Valuable Predictor for CPAP Adherence?

This study aim to evaluate if the improvement of heart rate variability for the continuous positive airway pressure titration night can predict the short and long term continuous positive airway pressure adherence for patients with moderate to severe OSA.

apnea-hypopnea index
continuous positive airway pressure
  • 22 Jan, 2021
  • 2 locations
Idiopathic Scoliosis Progression and Sleep-disordered Breathing in Children

This study aimed to investigate the prevalence and clinical significance of sleep-disordered breathing (SDB) in children with mild-moderate idiopathic scoliosis (IS).

  • 22 Jan, 2021
  • 1 location
Investigation of Sleep Quality and Prevalence of Sleep-disordered Breathing in Children and Young People With Epilepsy

Obstructive sleep apnoea (OSA) is a condition that affects around one in 20 children. In children with OSA, repeated episodes of airway obstruction can severely disturb and fragment sleep, leading to subsequent cognitive and behavioural problems . Epilepsy affects 60,000 children in the UK and up to 30% of children …

sleep disturbances
sleep-disordered breathing
airway obstruction
  • 27 Mar, 2021
  • 1 location
Obstructive Sleep Apnea Endotypes and Impact on Phenotypes of People Living With HIV

The investigators seek to understand how the different underlying causes of OSA affect the way people living with HIV (PLWH) experience OSA. The investigators also want to understand how symptoms of obstructive sleep apnea improve with treatment, and if this too, is affected by the underlying cause of OSA in …

HIV Vaccine
  • 26 Jan, 2021
  • 1 location
Correlation Between Nocturnal Oxygen Desaturation and Glycemic Control in Diabetic Patients With Obstructive Sleep Apnea

Nocturnal reduction in blood oxygen is expected independently associated with the development of worsened glycemic control in individuals with type 2 diabetes mellitus. The aim of the present study is to assess the correlation between nocturnal oxygen desaturation assessed by overnight pulse oximetry and glycemic control in diabetic patients with …

  • 27 Jan, 2021
  • 1 location
Natural History of Pompe Disease

The project is a prospective study in which patients affected by adult-onset Pompe disease with c.-32-13T>G mutation in the GAA gene will be followed-up during two years to describe the natural history using clinical, imaging, histological and molecular parameters. Secondary objectives are: To identify biomarkers for assessing efficacy of future …

walk test
gaa gene
  • 19 Feb, 2021
  • 2 locations
Subjective Sleep Quality and Sleep Disorders in Patients With Severe Asthma

Bronchial asthma is characterized by the presence of symptoms that vary over time and of severity. Asthma symptoms tend to worsen at night and in the early hours of the morning, and the presence of nocturnal symptoms is an important indicator of therapeutic intervention in order to control the severity …

persistent asthma
severe persistent asthma
  • 25 Jan, 2021
  • 1 location
Changes in Sleep Duration and Blood Pressure Across School Holiday in Teenagers

Our research question is: Are changes in sleep duration that occur naturally over school holidays associated with changes in blood pressure (BP) in sleep-deprived adolescents? In this study, the investigators will take advantage of changes in sleep duration that occur during school holidays in adolescents who are sleep deprived (>6 …

  • 05 Feb, 2021
  • 1 location