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Found 106 clinical trials
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Clinical Validation of At-Home Methods of Sleep Assessment in Rett Syndrome

There are two parts to this study. First, we want to determine the reliability of a wearable device for sleep quality in RTT against the gold-standard polysomnography. Additionally, we want

  • 0 views
  • 04 Oct, 2022
  • 1 location
Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group, Polysomnography, Dose-finding Study Assessing the Efficacy, Safety, and Pharmacokinetics of Multiple-dose Oral Administration of Daridorexant in Pediatric Subjects Aged 10 to < 18 Years With Insomnia Disorder

This study assesses the efficacy, safety, and pharmacokinetics of multiple-dose oral administration of daridorexant in pediatric subjects aged 10 to < 18 years with insomnia disorder.

terminal insomnia
poor sleep
chronic insomnia
selective serotonin reuptake inhibitors
  • 5 views
  • 25 Oct, 2022
  • 7 locations
Effect of High Flow Nasal Cannula Versus Continues Positive Airway Pressure in Adults With Obstructive Sleep Apnea

The participants whom undergo Polysomnography study (Sleep study) and are found to have mild, moderate or severe Obstructive Sleep Apnea (OSA) will have two consecutive titration nights

continuous positive airway pressure
obstructive sleep apnea
polysomnography
  • 0 views
  • 04 Oct, 2022
  • 1 location
The Efficacy of Continuous Positive Airway Pressure in Achieving Asthma Control in Patients With Severe Asthma and Obstructive Sleep Apnea

comorbid conditions such as GERD and obesity which negatively impact asthma control. Polysomnography is the study of sleep using different leads, heart rate and oxygen monitor to assess the architecture of

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Noninvasive Ventilation for Chronic Heart Failure

chronic stable heart failure were selected and monitored by polysomnography. Patients with sleep apnea hypopnea syndrome (SAHS, AHI15) were randomly divided into two groups: the treatment group was

  • 0 views
  • 12 Sep, 2021
  • 3 locations
Comparison of 2 Different Positional Therapies for Positional Obstructive Sleep Apnea Syndrome

The proposed study is a randomized cross over trial assessing the efficacy of two different positional therapies for positional obstructive sleep apnea (POSA). The effectiveness of the two different therapeutic devices (Positional pillow and vibrating belt) in reducing the time spent sleeping supine, and therefore at risk of apnoeas, will …

  • 32 views
  • 09 Sep, 2021
  • 1 location
Cannabinol Use in Patients With Insomnia Disorder (CUPID)

This study aims to investigate the acute effects of cannabinol (CBN) 30 mg and 300 mg, versus placebo, on sleep architecture and next-day functioning in adults aged 25-65 years with chronic insomnia disorder.

chronic insomnia
  • 0 views
  • 07 Oct, 2022
  • 1 location
Effect and Mechanism of HD-tDCS Combined With Circadian Rhythm Remodeling on Consciousness Recovery in Patients With Chronic Disorder of Consciousness (HD-tDCS)

The circadian rhythm characteristics of sleep cycle and neuroendocrine in patients with chronic disorder of consciousness show different degrees of disorder, and the relationship between this disorder and consciousness level is unclear.The researchers used HD-tDCS to treat patients with chronic disturbance of consciousness who intervened in circadian rhythm, and used …

  • 0 views
  • 20 Oct, 2022
  • 1 location
Epileptiform Activity During REM Sleep in Alzheimer's Disease (EREMAD)

Recent clinical data showed that patients with Alzheimer Disease (AD) might present epilepsy at early stages of the disease (Cretin et al., 2016, Vossel et al., 2016). In mice models of Alzheimer disease, preclinical researchers observed an increase of epileptic events during Rapid Eye Movement (REM) sleep, which is very …

polysomnography
apolipoprotein e
Accepts healthy volunteers
mental state examination
mini-mental state examination
  • 0 views
  • 23 Jan, 2022
  • 1 location
Alcohol and Neural Cardiovascular Control in Binge Drinkers

This study evaluates the impact of evening alcohol consumption on sympathetic activity and baroreflex function in binge drinkers. Our central hypothesis is that evening binge alcohol consumption will lead to sympathetic overactivity and blunted baroreflex function.

Accepts healthy volunteers
  • 13 views
  • 20 Apr, 2022
  • 1 location