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Found 86 clinical trials
Phenotype, Genotype and Biomarkers 2 (PGB2)

The purpose of this study is to learn more about amyotrophic lateral sclerosis (ALS) and other related neurodegenerative diseases, including frontotemporal dementia (FTD), primary lateral sclerosis (PLS), hereditary spastic paraplegia (HSP), progressive muscular atrophy (PMA) and multisystem proteinopathy (MSP). More precisely, the investigator wants to identify the links that exist …

progressive muscular atrophy
amyotrophic lateral sclerosis
Accepts healthy volunteers
  • 10 Jul, 2022
  • 4 locations
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one arm sufficient to perform daily activities. This study could lead to …

Accepts healthy volunteers
range of motion
neurological disorder
  • 05 Jul, 2022
  • 1 location
Analysis of the Instestinal Microbiome of Patients With Transthyretin Amyloidosis (AMIAT)

Amyloidosis is a serious systemic disease. Cardiac involvement has a great impact on prognosis and can occur in its three main forms: acquired monoclonal light chain, hereditary transthyretinal and senile form. The physiopathogenesis basically results from the deposition of an abnormal protein (amyloid) with toxic properties to the myocyte. The …

Accepts healthy volunteers
  • 25 Mar, 2022
  • 1 location
Inherited Retinal Degenerative Disease Registry (MRTR)

The My Retina Tracker Registry is sponsored by the Foundation Fighting Blindness and is for people affected by one of the rare inherited retinal degenerative diseases studied by the Foundation. It is a patient-initiated registry accessible via a secure on-line portal at Affected individuals who register are guided to …

Accepts healthy volunteers
degenerative disease
other disease
genetic testing
  • 25 Jan, 2022
  • 1 location
Sensory Abnormalities in Post-surgical Peripheral Neuropathy

The concept of normality is a cornerstone in medical practice and research. As an example, in clinical chemistry, a laboratory value based on a patient plasma sample, exceeding the +/- 1.96 x standard deviation (SD) range, referenced from a normative material, is per definition outside the normal range (the reference …

body mass index
Accepts healthy volunteers
  • 24 Mar, 2022
  • 1 location
Screening Patients With Diabetes Mellitus for the Presence of Skin Disorder of Scleredema

Scleredema is a scleroderma-like skin disorder appearing in 2.5-14% among patients with type 1 or 2 diabetes mellitus. This is a single centre study to screen consecutive patients with diabetes mellitus for the presence of scleredema,and to compare the clinical-laboratory data of patients with and without scleredema. Metabolic and vascular …

diabetes mellitus
  • 03 Mar, 2022
  • 1 location