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Found 87 clinical trials
Peripheral Nerve Block in Patients With Painful Diabetic Polyneuropathy

The purpose of the present study is to evaluate the role of peripheral afferent input for spontaneous pain in painful diabetic polyneuropathy

  • 27 Jan, 2021
  • 1 location
A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

The purpose of this study is to evaluate the safety and tolerability of extended dosing with Eplontersen in participants with hereditary transthyretin-mediated amyloid polyneuropathy (hATTR-PN

  • 23 Apr, 2022
  • 2 locations
The Effect of Tafamidis on Transthyretin Stabilization Safety Tolerability and Efficacy in Transthyretin Amyloid Polyneuropathy Patients

Transthyretin amyloid polyneuropathy (ATTR-PN) is a fatal illness resulting from autosomal dominantly inherited single-point mutations on the transthyretin gene. Tafamidis is a specific

  • 23 Jul, 2021
  • 1 location
  • 06 Jan, 2022
  • 3 locations
Cryotherapy vs. Cryocompression for Preventing Chemotherapy-induced-peripheral-neuropathy in Women Undergoing Chemotherapy

benefits with additional compression to the cryotherapy are reduction of chemotherapy induced polyneuropathy and reduced nail changes.

  • 26 Jan, 2021
  • 1 location
Subcutaneous Immunoglobulin in De-novo CIDP (SIDEC)

SIDEC - (Subcutaneous Immunoglobulin in De-novo CIDP) ia a study designed as a randomized, parallel study with an open-label extension phase. The aims are to compare the effect of SCIG and IVIG in 60 treatment-nave CIDP patients, and to detect the lowest effective dosage for maintenance treatment.

  • 25 Jan, 2021
  • 4 locations
A First in HumanTrial to Evaluate The Safety, Tolerability, And Pharmacokinetics Of PF-06755347

This phase 1 single ascending dose study will provide a first in human assessment of safety and tolerability of PF-06755347 in healthy adult males as well as adult males and females with Immune Thrombocytopenia (ITP). Pharmacokinetics and pharmacodynamics will also be evaluated.

progressive systemic sclerosis
immune globulin
administered intravenously
heart failure
  • 26 Mar, 2022
  • 3 locations
Single vs. Multiple Privigen Dose Regimens in Pediatric CIDP

A randomized, open-label, prospective, multicenter study designed to investigate 2 dose regimens in pediatric subjects 2 to < 17 years of age with confirmed or possible CIDP, either previously exposed to IVIG treatment or unexposed to IVIG treatment

  • 13 Apr, 2022
  • 9 locations
HepatoPredict Prognostic Tool for the Decision of Liver Transplant in Hepatocellular Carcinoma (HepatoPredict)

will be transplanted with marginal livers or with livers from patients with Familial Amyloid Polyneuropathy, not competing with patients on the waiting list. Patients will be followed up to 60 months

  • 14 Jun, 2022
  • 1 location
Neuromuscular Electrical Stimulation For The Treatment of Diabetic Peripheral Neuropathy (NMES for DPN)

Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, affecting almost 50% of people with diabetes over the course of their lives. Symptoms vary from numbness to burning, aching and hypersensitivity in the lower limbs, indicative of sensory nerve loss. Motor neurons can also be affected, leading to …

nerve conduction
nerve conduction study
peripheral neuropathy
nerve conduction studies
  • 23 Mar, 2022
  • 1 location