Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 54 clinical trials
featured
Myelofibrosis

Myelofibrosis

  • 532 views
  • 08 Nov, 2020
  • 1 location
The TAPS Trial - Fetoscopic Laser Surgery for Twin Anemia Polycythemia Sequence

with twin anemia-polycythemia sequence. Half op the patients will be treated with fetoscopic laser surgery, while the other half will be managed with standard treatment. The hypothesis is that

  • 0 views
  • 25 Jan, 2021
  • 4 locations
MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polcythemia Vera

The trial will be a phase III, randomised-controlled, multi-centre, international, open-label trial consisting of ruxolitinib versus best available therapy, where best available therapy is a choice of interferon alpha, any formulation permitted (IFN) or hydroxycarbamide (HC), and which will be elected by the Investigator prior to randomisation.

interferon
ruxolitinib
hydroxyurea
  • 0 views
  • 24 Jan, 2021
  • 2 locations
Hepcidin Mimetic in Patients With Polycythemia Vera

and to obtain preliminary evidence of efficacy of PTG-300 for the treatment of phlebotomy-requiring polycythemia vera.

interferon
ruxolitinib
phlebotomy
hydroxyurea
  • 8 views
  • 26 Jan, 2021
  • 17 locations
Clinical Efficacy of Erythropheresis in High Altitude Polycythemia

The clinical study is aimed to explore the efficacy and safety of erythropheresis in high altitude polycythemia.

  • 0 views
  • 08 Apr, 2021
  • 1 location
Erythropoietin in Premature Infants to Prevent Encephalopathy

The main goal of this trial is to investigate whether early administration of human erythropoietin (EPO) in preterm infants improves neurodevelopmental outcome at 18 months corrected age. This study is designed as randomized, double-masked, placebo controlled multicenter study involving at least 312 patients.

  • 0 views
  • 15 Mar, 2021
  • 1 location
A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis Post Polycythemia Vera Myelofibrosis or Post-Essential Thrombocythemia Myelofibrosis

) Condition or disease: Primary Myelofibrosis/Post-Polycythemia Vera Myelofibrosis/ Post-essential Thrombocythemia Myelofibrosis Intervention/treatment: Drug-Pacritinib

blood blast count
ct scan
thrombocytosis
neutrophil count
myelofibrosis
  • 506 views
  • 21 Aug, 2021
  • 178 locations
An Efficacy and Safety Study of Fedratinib Compared to Best Available Therapy in Subjects With DIPSS-intermediate or High-risk Primary Myelofibrosis Post-polycythemia Vera Myelofibrosis or Post-essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib

Prognostic Scoring System)-intermediate or high-risk primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (post-PV MF), or post-essential thrombocythemia myelofibrosis (post-ET MF) and

cancer
thrombocytosis
thrombocytopenia
anemia
polycythemia
  • 103 views
  • 28 Aug, 2021
  • 125 locations
To Assess the Safety Tolerability and Efficacy of Itacitinib Immediate Release Tablets in Participants With Primary or Secondary Myelofibrosis Who Have Received Prior Ruxolitinib and/or Fedratinib Monotherapy (LIMBER-213)

This is a 2-part study. In Part 1, participants will be dosed at 2 different dose levels in order to select the RP2D for Part 2 of the study.

ruxolitinib
myelofibrosis
  • 0 views
  • 08 Aug, 2021
  • 12 locations
Study of CPI-0610 in Myelofibrosis (MF)

A Phase 3, randomized, blinded study comparing CPI-0610 and ruxolitinib with placebo and ruxolitinib in myelofibrosis (MF) patients that have not been exposed previously to Janus kinase inhibitors (JAKi). CPI-0610 is a small molecule inhibitor of bromodomain and extra-terminal (BET) proteins. Evidence suggests that inhibition of both BET and JAK …

  • 0 views
  • 19 Sep, 2021
  • 47 locations