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Found 3 clinical trials
177Lu-PSMA-617 vs. Androgen Receptor-directed Therapy in the Treatment of Progressive Metastatic Castrate Resistant Prostate Cancer

The purpose of this study is to determine whether 177Lu-PSMA-617 improves the rPFS or death compared to a change in ARDT in mCRPC participants that were previously treated with an alternate ARDT and not exposed to a taxane-containing regimen in the CRPC or mHSPC settings. Approximately 450 participants will be …

  • 0 views
  • 01 Aug, 2021
  • 16 locations
Dose Escalation and Cohort Expansion Study of Niraparib and Dostarlimab in Pediatric Participants With Solid Tumors

This study will evaluate the combination of a poly (adenosine diphosphate-ribose) polymerase (PARP) inhibitor, niraparib, with the programmed cell death protein 1 (PD-1) inhibitor, dostarlimab

breast cancer
carcinoma
primary cancer
solid tumor
sarcoma
  • 0 views
  • 01 Aug, 2021
  • 10 locations
Olaparib + Sapacitabine in BRCA Mutant Breast Cancer

This research study is studying a combination of drugs as a possible treatment for breast cancer with a BRCA mutation. The interventions involved in this study are: Sapacitabine (CYC682) Olaparib (Lynparza)

erbb2
metastasis
endocrine therapy
immunostimulant
estrogen
  • 67 views
  • 27 Jan, 2021
  • 1 location