Found 484 clinical trials
Serotype 3 Experimental Human Pneumococcal Challenge; Dose Ranging and Reproducibility in a Healthy Volunteer Population (Challenge3)
The 'Experimental Human Pneumococcal challenge' (EHPC) model is a way of putting drops of bacteria into the nose. Investigators have studied this model of putting bacteria in the nose safely in over 1500 volunteers over the past decade with no serious side effects and now want to test the model …
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- 18 Oct, 2022
- 1 location
Defibrotide for the Treatment of Severe COVID-19
The goal of this study is to evaluate the safety and feasibility of defibrotide in COVID-19 pneumonia.
- 1 views
- 07 Aug, 2021
- 1 location
Evaluate the Efficacy and Safety of TF0023 in Treatments for COVID-19 in Hospitalized Adults
Techfields Inc. is developing a new investigational prodrug as a topical spray, indicated for relief of the signs and symptoms of ARDS and pneumonia caused by COVID-19. This is a Phase 2
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- 05 Jun, 2022
- 1 location
Dynamic Change and Immune Response to Nasopharyngeal Carriage and Acute Otitis Media Pathogens
antibiotic-resistant Streptococcus pneumoniae (Spn) and Haemophilus influenzae (Hflu).
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- 23 Jul, 2021
- 1 location
Double-blind, Randomized, Placebo-controlled Trial to Evaluate the Safety and Efficacy of Atorvastatin to Reduce Inflammation After Tuberculosis Treatment Completion in HIV-infected and HIV-uninfected Adults Measured by FDG-PET/CT (StatinTB)
This is a proof-of-concept phase IIB, double-blind, randomized, placebo-controlled trial to evaluate the safety and efficacy of 40 mg atorvastatin to reduce persistent lung inflammation after
- 0 views
- 29 Oct, 2022
- 1 location
Functional Lung Avoidance Radiation Therapy Using Hyperpolarized Xenon-129 MRI
treatment plans based on this novel imaging modality could reduce risk or severity of radiation pneumonitis and improve post-treatment quality of life.
- 0 views
- 25 Apr, 2022
- 1 location
The Influence of Polymeric Versus Oligomeric Enteral Feeding on Tolerance and Nutritional Status in Paediatric Intensive Care (Polygomer)
pneumonia. The optimization of enteral feeding tolerance is therefore one of the research priorities. Implementation of feeding protocols is associated with better tolerance. The enteral feeding could be
- 0 views
- 04 Oct, 2022
- 1 location
RejuvenAir® System Trial for COPD With Chronic Bronchitis (SPRAY-CB)
developing pneumonia, reduced health related quality of life, and an increase in all-cause mortality.
- 428 views
- 29 Jun, 2022
- 22 locations
Can the Relative Fecal Abundance of BLSE and the Digestive Microbiota be Predictive of the Risk of Infection in a Carrier Patient? (CORPOBLSE2)
Klebsiella pneumoniae (K. pneumoniae) has increased dramatically. The emergence of multidrug-resistant Enterobacteriaceae is currently a real public health problem. The European Antimicrobial
- 0 views
- 04 Oct, 2022
- 1 location
Clinical Study on Autologous Platelet-rich Plasma (PRP) Treatment for Tracheobronchial Fistula
and tracheobronchioesophageal fistulas are two common types og TBF, which are mainly manifested as choking on eating and repeated aspiration pneumonia. Respiratory intervention has become one of the
- 0 views
- 24 Apr, 2022
- 1 location