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Found 451 clinical trials
Featured trial
Pneumococcal Infection

The purpose of this study is to evaluate the concomitant and non-concomitant use of messenger ribonucleic acid (mRNA) mRNA-1273, the nucleoside-modified mRNA vaccine for active immunization to prevent coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), with a 23-valent pneumococcal polysaccharide vaccine for the prevention of pneumococcal …

covid-19
polysaccharide
  • 0 views
  • 18 Apr, 2022
  • 1 location
Featured trial
Pneumonia Vaccine

Are you due for a pneumonia vaccine and a COVID Booster? The team at AMR Kansas City are now enrolling healthy volunteers in an investigational pneumonia vaccine clinical research study.&nbsp

Accepts healthy volunteers
booster
pneumonia
  • 247 views
  • 23 Dec, 2021
  • 1 location
Featured trial
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Investigational Product in Patients With Rheumatoid Arthritis (RA) With or Without Background Disease-Modifying Anti-rheumatic Drug (DMARD) Therapy

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Investigational Product in Patients With Rheumatoid Arthritis (RA) With or Without Background Disease-Modifying Anti-rheumatic Drug (DMARD) Therapy

  • 816 views
  • 08 Nov, 2020
  • 1 location
Pneumocystis Pneumonia Diagnosis in HIV- Patients (PNEUMOQUANT)

Pneumocystis jirovecii pneumonia is a serious and frequent infection in immunocompromised patients, whose evolution is potentially fatal if untreated. It is the most common opportunistic

cytostatics
early diagnosis
mechanical ventilation
immunodeficiency
HIV Infection
  • 3 views
  • 09 May, 2022
  • 3 locations
Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia (PreVent2)

Researchers are looking at two different types of breathing tubes to see if one is better than the other at preventing pneumonia. One of the tubes has a design features to prevent leakage of

intubation
  • 68 views
  • 06 Feb, 2022
  • 1 location
  • 0 views
  • 09 Apr, 2023
  • 1 location
PROcalcitonin Impact on Antibiotic Reduction, adverSe Events and AVoidable healthcarE Costs (ProSAVE): A RCT (ProSAVE)

Trials comparing PCT-guided antibiotic algorithms to standard management show a significant reduction in antibiotic exposure without an increase in mortality or treatment failure. Despite this strong evidence from multiple studies a recent prospective multicentric interventional trial in the US fell short of demonstrating antibiotic reductions by PCT-guided antibiotic management. Amongst …

antibiotic therapy
procalcitonin
antibiotics
community acquired pneumonia
  • 23 views
  • 03 Apr, 2023
  • 4 locations
Efficacy and Safety Evaluation of Paxlovid for COVID-19: a Real-world Case-control Study

COVID-19 is currently one of the serious public health challenges worldwide, and there is a great need to develop effective treatments. Paxlovid is a Pfizer-developed oral new drug for the treatment of COVID-19. Paxlovid, which is used to treat adult patients with mild to moderate COVID-19 who have high-risk factors …

  • 0 views
  • 07 Oct, 2022
  • 1 location
Efficacy of DEXamethasone in Patients With Acute Hypoxemic REspiratory Failure Caused by INfEctions (DEXA-REFINE)

spectrum of AHRF ranges from mild respiratory tract illness to severe pneumonia, acute respiratory distress syndrome (ARDS), multiorgan failure, and death. The efficacy of corticosteroids in AHRF and ARDS

  • 0 views
  • 10 Apr, 2022
Improving Care Through Azithromycin Research for Infants in Africa

die each year, the leading causes being neonatal conditions, malaria, pneumonia and diarrhea. In Sierra Leone, the available information on malaria indicates that it accounts for 38% of deaths among

  • 0 views
  • 21 Sep, 2021
  • 1 location