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Found 6 clinical trials
Mass Campaigns With Fractional Dose Pneumococcal Vaccines in Sub-Saharan Africa (fPCV) (fPCV)

The aim of this study is to assess the impact of a mass campaign with a single, fractional dose of Pneumosil®, a PCV10, on VT carriage. A 20% fractional dose (1/5th) will be used as a practical formulation to prepare and administer. This study will assess whether the impact of …

Accepts healthy volunteers
  • 0 views
  • 17 Jun, 2022
  • 1 location
Twice Daily Treatment With Amoxicillin for Non-severe Community Acquired Pneumonia.

The aim of this study will be to evaluate whether a twice-daily antibiotic regimen is non-inferior to a thrice-daily regimen for the treatment of non-severe community acquired pneumonia in

chest x-ray
Accepts healthy volunteers
antibiotic therapy
antibiotics
fever
  • 8 views
  • 18 May, 2022
  • 1 location
Severe Pneumonia In Children (S-PIC) Study: A Comparative Effectiveness Study Of Children With Severe Pneumonia In Asia

Severe pneumonia is a leading cause of mortality and morbidity in children worldwide. Mortality rates from pediatric severe pneumonia are three times higher in South East Asia compared to the Western hemisphere. The lack of description of epidemiology, current management strategies and outcomes of children with severe pneumonia admitted to …

chest pain
hypothermia
respiratory failure
fever
pneumonia
  • 0 views
  • 18 Apr, 2022
  • 1 location
Pneumonia Research and Vaccine Impact League

The leading cause of severe respiratory disease and death in young children is Streptococcus pneumoniae (pneumococcus). An estimated one-fifth of global childhood pneumococcal-related deaths occurred in India. The pneumococcal conjugate vaccine (PCV) is a primary prevention tool against pneumococcal disease that is safe and effective and has been in use …

  • 0 views
  • 26 Jan, 2021
  • 1 location
PCV13 Impact on Pneumococcal Nasopharyngeal Carriage Study (IMPACT)

Prospective, observational, hospital based, nasopharyngeal carriage (NPC), vaccine effectiveness study Comparisons will be made in Filipino children, aged 8 weeks to ≤60 months of age at enrollment, who have been hospitalized with a radiologically-confirmed, community-acquired pneumonia (CAP).

  • 0 views
  • 10 Mar, 2022
  • 1 location
Population Pharmacokinetics of Cephalosporins and Macrolides in Chinese Children With Community Acquired Pneumonia

This study is based on the hypothesis that the pharmacokinetics of antibiotics in children is different from adults. Cephalosporins and macrolide antibiotics are the common drugs for children with community acquired pneumonia, the investigators aim to study the population pharmacokinetics of cephalosporins and macrolide antibiotics in children receiving the drug …

x-rays
macrolides
purulent sputum
chest pain
antibiotic therapy
  • 0 views
  • 21 Jan, 2021