Found 951 clinical trials
Sanofi COVID Booster Study
The primary objectives of the study are: To assess the safety profile of the study vaccines in each study intervention group. To assess the neutralizing antibody profile after primary series vaccination in SARS-CoV-2-nave adults. To demonstrate that a booster dose of monovalent or bivalent SARS-CoV-2 vaccine given to adults previously …
- 972 views
- 16 Sep, 2021
- 2 locations
VAD00001: Respiratory Syncytial Virus (RSV) Study
The primary objectives of the study are: To assess the safety profile of each dose of the study product after each and any administration in all infants and toddlers regardless of baseline neutralizing antibody serostatus. To characterize the RSV-A serum neutralizing antibody responses to the study product in each vaccine …
- 51 views
- 10 Sep, 2021
- 17 locations
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Investigational Product in Patients With Rheumatoid Arthritis (RA) With or Without Background Disease-Modifying Anti-rheumatic Drug (DMARD) Therapy
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Investigational Product in Patients With Rheumatoid Arthritis (RA) With or Without Background Disease-Modifying Anti-rheumatic Drug (DMARD) Therapy
- 167 views
- 08 Nov, 2020
- 1 location
Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia
Researchers are looking at two different types of breathing tubes to see if one is better than the other at preventing pneumonia. One of the tubes has a design features to prevent leakage of
- 0 views
- 29 May, 2021
- 2 locations
Leronlimab in Moderately Ill Patients With COVID-19 Pneumonia
study is to assess the safety and efficacy of leronlimab plus standard of care in patients hospitalized with COVID-19 pneumonia who are not requiring mechanical ventilation or extracorporeal oxygenation
- 0 views
- 20 Sep, 2021
- 16 locations
PROcalcitonin Impact on Antibiotic Reduction adverSe Events and AVoidable healthcarE Costs (ProSAVE): A RCT
Trials comparing PCT-guided antibiotic algorithms to standard management show a significant reduction in antibiotic exposure without an increase in mortality or treatment failure. Despite this strong evidence from multiple studies a recent prospective multicentric interventional trial in the US fell short of demonstrating antibiotic reductions by PCT-guided antibiotic management. Amongst …
- 0 views
- 26 Jan, 2021
- 2 locations
Single-dose PK Study of Ceftazidime-Avibactam In Hospitalized Children Receiving Systemic Antibiotics for Nosocomial Pneumonia
intravenous dose of CAZ AVI in pediatric subjects aged 3 months to less than 18 years who are receiving systemic antibiotic therapy for suspected or confirmed nosocomial pneumonia, including ventilator
- 15 views
- 02 Jul, 2021
- 59 locations
Effectiveness Trial of Day-care vs. Usual Care of Severe Pneumonia & Malnutrition in Children
Background: At present pneumonia and malnutrition have become the leading causes of mortality among <5-year-old children in developing countries. World Health Organization standard management
- 2 views
- 04 Jun, 2021
- 2 locations
Study Comparing Inhaled Amikacin Versus Placebo to Prevent Ventilator Associated Pneumonia
The objective of the study is to prove that after the third day of invasive mechanical ventilation a three-day course of inhaled amikacin reduces the incidence of subsequent VAP. Parallel two group double blind randomized controlled clinical trial. Individual randomization, performed on day 4 of invasive mechanical ventilation, will be …
- 3 views
- 01 Mar, 2021
- 42 locations
WGS-guided Tracking and Infection Control Measures of CRKP
The objective of this study is to investigate the effect of the infection control measures based on the active screening of carbapenem-resistant Klebsiella pneumoniae and whole-genome based
- 0 views
- 25 Jan, 2021
- 1 location