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Found 948 clinical trials
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A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Investigational Product in Patients With Rheumatoid Arthritis (RA) With or Without Background Disease-Modifying Anti-rheumatic Drug (DMARD) Therapy

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Investigational Product in Patients With Rheumatoid Arthritis (RA) With or Without Background Disease-Modifying Anti-rheumatic Drug (DMARD) Therapy

  • 156 views
  • 08 Nov, 2020
  • 1 location
featured
Pneumococcal & Flu Vaccine Study for Seniors

The purpose of this study is to learn about the safety (side effects) and amount of antibodies made after vaccination (immune response) in adults 65 years of age and older when an investigational pneumococcal vaccine is given at the same time as an influenza vaccine is given or when the …

vaccination
trivalent influenza vaccine
pneumococcal
pneumococcal polysaccharide vaccine
influenza
  • 40 views
  • 23 Nov, 2020
  • 1 location
Pneumocystis Pneumonia Diagnosis in HIV- Patients

Pneumocystis jirovecii pneumonia is a serious and frequent infection in immunocompromised patients, whose evolution is potentially fatal if untreated. It is the most common opportunistic

cancer
early diagnosis
mechanical ventilation
bronchoalveolar lavage
AIDS
  • 3 views
  • 24 Jan, 2021
  • 3 locations
Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia

Researchers are looking at two different types of breathing tubes to see if one is better than the other at preventing pneumonia. One of the tubes has a design features to prevent leakage of

intubation
  • 0 views
  • 26 Jan, 2021
  • 2 locations
PROcalcitonin Impact on Antibiotic Reduction adverSe Events and AVoidable healthcarE Costs (ProSAVE): A RCT

Trials comparing PCT-guided antibiotic algorithms to standard management show a significant reduction in antibiotic exposure without an increase in mortality or treatment failure. Despite this strong evidence from multiple studies a recent prospective multicentric interventional trial in the US fell short of demonstrating antibiotic reductions by PCT-guided antibiotic management. Amongst …

antibiotic therapy
community acquired pneumonia
antibiotics
procalcitonin
  • 0 views
  • 26 Jan, 2021
  • 2 locations
Study Comparing Inhaled Amikacin Versus Placebo to Prevent Ventilator Associated Pneumonia

The objective of the study is to prove that after the third day of invasive mechanical ventilation a three-day course of inhaled amikacin reduces the incidence of subsequent VAP. Parallel two group double blind randomized controlled clinical trial. Individual randomization, performed on day 4 of invasive mechanical ventilation, will be …

mechanical ventilation
antibiotics
antibiotic therapy
  • 3 views
  • 01 Mar, 2021
  • 42 locations
Single-dose PK Study of Ceftazidime-Avibactam In Hospitalized Children Receiving Systemic Antibiotics for Nosocomial Pneumonia

intravenous dose of CAZ AVI in pediatric subjects aged 3 months to less than 18 years who are receiving systemic antibiotic therapy for suspected or confirmed nosocomial pneumonia, including ventilator

  • 0 views
  • 19 Feb, 2021
  • 45 locations
WGS-guided Tracking and Infection Control Measures of CRKP

The objective of this study is to investigate the effect of the infection control measures based on the active screening of carbapenem-resistant Klebsiella pneumoniae and whole-genome based

  • 0 views
  • 25 Jan, 2021
  • 1 location
Efficacy Safety and Tolerability of ATM-AVI in the Treatment of Serious Infection Due to MBL-producing Gram-negative Bacteria

intra-abdominal infections (cIAI), nosocomial pneumonia (NP) including hospital acquired pneumonia (HAP) and ventilator associated pneumonia (VAP), complicated urinary tract infections (cUTI), or

  • 0 views
  • 30 Jan, 2021
  • 31 locations
Prevalence and Impact of COVID-19 Infection in Pregnant Women Fetuses and Newborns

responsible for a mild infectious syndrome, but patients can also develop pneumonia, acute respiratory failure and other serious complications. To date, very little and controversial literature is available

  • 12 views
  • 26 Jan, 2021
  • 1 location