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Found 25 clinical trials
Featured trial
ALTE07C1: Neuropsychological and Behavioral Testing in Young Patients with Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET)

ALTE07C1: Neuropsychological and Behavioral Testing in Young Patients with Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET)

  • 16 views
  • 08 Nov, 2020
  • 1 location
Featured trial
ACNS0821:Temozolomide With Irinotecan Versus Temozolomide, Irinotecan Plus Bevacizumab (NSC# 704865, BB-IND# 7921) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood, A COG Randomized Phase II Screening Trial

ACNS0821:Temozolomide With Irinotecan Versus Temozolomide, Irinotecan Plus Bevacizumab (NSC# 704865, BB-IND# 7921) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood, A COG Randomized

  • 112 views
  • 08 Nov, 2020
  • 1 location
Featured trial
  • 361 views
  • 08 Nov, 2020
  • 1 location
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), or Von Hippel-Lindau (VHL) Disease-Associated Tumors (MK-6482-015)

This is a study to evaluate the efficacy and safety of Belzutifan monotherapy in participants with advanced pheochromocytoma/paraganglioma (PPGL), pancreatic neuroendocrine tumor (pNET) or von

  • 0 views
  • 27 Jun, 2022
  • 37 locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

>Adenocarcinoma with variants of GU system (excluding prostate cancer) (closed to accrual 07/27/2018) Odontogenic malignant tumors Pancreatic neuroendocrine tumor (PNET) (formerly named

chordoma
mullerian mixed tumor
carcinosarcoma
octreotide
pheochromocytoma, malignant
  • 6632 views
  • 29 Jun, 2022
  • 759 locations
Precision Radiotherapy Using MR-linac for Pancreatic Neuroendocrine Tumours in MEN1 Patients (PRIME)

Patients with the Multiple Endocrine Neoplasia type 1 (MEN1) syndrome are genetically predisposed for developping multiple pancreatic neuro-endocrine tumours (pNET). The management of small

  • 0 views
  • 16 Jun, 2022
  • 1 location
Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

25 years, with relapsed or refractory ependymoma, medulloblastoma/PNET, or glioblastoma that progressed after previous treatment with indoximod plus temozolomide. Those previously treated with

MRI
neutrophil count
cytotoxic chemotherapy
renal function
tyrosine
  • 0 views
  • 23 Apr, 2022
  • 1 location
Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors (PNOC025)

intrinsic pontine glioma (DIPG), high-grade glioma (adult and pediatric), medulloblastoma, and embryonal tumors formerly called Primitive Neuro-Ectodermal Tumors (PNET). Safety studies in humans have proven

  • 0 views
  • 29 May, 2022
  • 1 location
HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors

This is a Phase 1 study of central nervous system (CNS) locoregional adoptive therapy with autologous CD4 and CD8 T cells lentivirally transduced to express a HER2-specific chimeric antigen receptor (CAR) and EGFRt, delivered by an indwelling catheter in the tumor resection cavity or ventricular system in children and young …

viral therapy
MRI
tumor resection
tumour resection
cns disease
  • 68 views
  • 17 Mar, 2022
  • 1 location
EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors

This is a Phase 1 study of central nervous system (CNS) locoregional adoptive therapy with autologous CD4+ and CD8+ T cells that are lentivirally transduced to express an EGFR806 specific chimeric antigen receptor (CAR) and EGFRt. CAR T cells are delivered via an indwelling catheter into the tumor cavity or …

cns neoplasm
cns tumor
viral therapy
MRI
tumor resection
  • 3 views
  • 25 Mar, 2022
  • 1 location