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Found 167 clinical trials
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A Phase 2 Study of INCMGA00012 in Participants With Squamous Carcinoma of the Anal Canal Who Have Progressed Following Platinum-Based Chemotherapy

platinum-based chemotherapy.

measurable disease
platinum-based chemotherapy
chemotherapy regimen
  • 62 views
  • 23 Nov, 2020
  • 24 locations
featured
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Niraparib Maintenance Treatment in Patients with Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Niraparib Maintenance Treatment in Patients with Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based

  • 1940 views
  • 23 Nov, 2020
  • 106 locations
featured
A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression On or After Platinum-Based Chemotherapy and Checkpoint Inhibitor Therapy (SAPPHIRE)

docetaxel in patients with advanced non-squamous NSCLC who have previously experienced radiographic disease progression on or after treatment with platinum-based chemotherapy in combination with CIT.

non-squamous non-small cell lung cancer
cancer
advanced non-squamous non-small cell lung cancer
advanced lung cancer
lung cancer
  • 199 views
  • 07 Jan, 2021
  • 109 locations
featured
A Randomized, Double Blind, Phase 3 Study of Platinum-Based Chemotherapy With or Without INCMGA00012 in First-Line Metastatic Squamous and Nonsquamous Non–Small Cell Lung Cancer.

The purpose of this study is to assess the efficacy and safety of platinum-based chemotherapy with or without INCMGA00012 in participants with metastatic squamous and nonsquamous non–small

platinum-based chemotherapy
lung carcinoma
cancer
cancer chemotherapy
measurable disease
  • 12 views
  • 14 Dec, 2020
  • 1 location
featured
A Phase III, Randomised, Double Blind, Placebo Controlled, Multicentre Study of Maintenance Olaparib Monotherapy in Patients With gBRCA Mutated Metastatic Pancreatic Cancer Whose Disease Has Not Progressed on First Line Platinum Based Chemotherapy

Progressed on First Line Platinum Based Chemotherapy

  • 326 views
  • 08 Nov, 2020
  • 27 locations
featured
A Phase 2 Study of Sitravatinib in Combination with Nivolumab in Patients with Advanced or Metastatic Urothelial Carcinoma (516-003)

cohorts based upon the following: Whether or not patients were previously treated with or were ineligible for platinum-based chemotherapy  Whether or not patients were

metastatic urothelial carcinoma
cancer
advanced urothelial cancer
platinum-based chemotherapy
nivolumab
  • 80 views
  • 23 Dec, 2020
  • 1 location
Study of GSK3359609 With Pembrolizumab and 5-fluorouracil (5-FU)-Platinum Chemotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

The purpose of this study is to evaluate if the addition of GSK3359609 to pembrolizumab in combination with 5FU-platinum based chemotherapy improves the efficacy of the pembrolizumab combination

squamous cell carcinoma of head and neck
carboplatin
primary tumor
dental caries
human papillomavirus
  • 0 views
  • 17 Jan, 2021
  • 52 locations
Atezolizumab With Bevacizumab and Chemotherapy vs Bevacizumab and Chemotherapy in Early Relapse Ovarian Cancer

and chemotherapy in patients with recurrent ovarian-, fallopian tube, or primary peritoneal cancer with 1st or 2nd relapse within 6 months after platinum based chemotherapy or 3rd relapse.

  • 65 views
  • 12 Jan, 2020
  • 75 locations
Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab Followed by Maintenance Durvalumab Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients.

This is a Phase III randomised, double-blind, multi-centre study to evaluate the efficacy and safety of durvalumab in combination with standard of care platinum based chemotherapy and

  • 84 views
  • 17 Jan, 2021
  • 281 locations
Platino-resistance in Ovarian Cancer

Prospective, monocentric study aiming to identify factors involved in platinum based-chemotherapy resistance in patients with epithelial ovarian cancer (all stages). Patients will

ovarian cancer
ascites
  • 0 views
  • 14 May, 2020
  • 1 location