Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 108 clinical trials
Dynamics of Platelet Activation in Patients With Ventricular Assist Device (VAD) (PASVAD)

Consenting patients with end-stage heart failure that are implanted with/candidates for implant of a short-term/durable mechanical circulatory support device (e.g.: percutaneous microaxial pumps (Impella), extracorporeal membrane oxygenator (ECMO), Ventricular Assist Device (VAD) will be enrolled in the study. Aim of the study is to evaluate the patients' haemostatic and coagulation …

coagulation test
hemostatic
heart failure
Accepts healthy volunteers
  • 0 views
  • 17 May, 2022
  • 1 location
Post-Injury Platelet Biology: Mechanisms and Outcomes

Trauma-induced coagulopathy is a central cause of preventable deaths from hemorrhage after injury. The contribution and impact of altered post injury platelet biology on trauma-induced coagulopathy is not well understood despite the pivotal contribution of platelets to normal coagulation and endothelial integrity. The central hypothesis for this study is that …

Accepts healthy volunteers
  • 3 views
  • 22 Oct, 2022
  • 1 location
Medication Use Evaluation for Enoxaparin in Hospitalized COVID-19 Patients

Retrospective chart review to be conducted at Methodist Richardson Medical Center (MRMC) in Richardson, TX. All adult patients hospitalized with COVID-19 on enoxaparin for DVT prophylaxis will be included. Collected data will be analyzed to determine the safety and effectiveness of the varying enoxaparin doses, and results will be presented …

enoxaparin
covid-19
  • 0 views
  • 24 Mar, 2022
  • 1 location
Skeletal and Respiratory Muscle Strength, Pulmonary Function, Exercise Capacity and Physical Activity in Pediatric Chronic Kidney Disease

Studies examining musculoskeletal strength, respiratory function and muscle strength, physical activity level and exercise capacity in children with CKD and evaluating the relationships between these parameters have not been found both in the world and in our country. In this study, it is aimed to evaluate skeletal and respiratory muscle …

Accepts healthy volunteers
arterial stiffness
  • 0 views
  • 12 May, 2022
  • 1 location
Characterization of the Platelet Inflammatory Response in NAFL and NASH

The primary objective of the study is to identify which features of platelet activation promote the inflammatory response that underlies the progression from NAFL to NASH. Therefore, the investigators plan: To characterize and compare the platelet inflammatory phenotype in NAFL vs NASH patients To study if and how the signaling …

  • 0 views
  • 22 Mar, 2022
  • 1 location
EUS Elastography for Predicting Cirrhotic-related Complications

Evaluation of the tissue stiffness as a surrogate marker of degree of liver cirrhosis has gained popularity in recent decades. Current guidelines also advocate the use of Fibroscan® machine (EchoSens, Paris, France) to detect any advanced liver fibrosis as represented by high liver stiffness, for prediction of varices development. Apart …

stiffness
varicose veins
fibroscan
cirrhosis
liver disease
  • 0 views
  • 25 Mar, 2022
  • 1 location
Volume Resuscitation in Cirrhosis With Sepsis Induced Hypotension

In critically ill patients with liver disease like cirrhosis or ACLF, fluid therapy needs to be instituted after identification of patients who will be fluid responsive and initiate appropriate inotropes early to prevent the mortality associated with fluid overload. The parameters and methodology used for assessing fluid responsiveness have been …

resuscitation
liver disease
systolic blood pressure
  • 0 views
  • 06 Jun, 2022
  • 2 locations
Predicting Relapse of Ulcerative Colitis With Gastrointestinal Ultrasound (PRELAPSE)

Rationale Ulcerative colitis (UC) is remitting disease with a variable course. Predicting disease relapse after remission is important for the adjustment of medical treatment. Ileocolonoscopy is the best tool for doing this, but due to its invasiveness should be replaced by a method better accepted by the patient. Gastrointestinal ultrasound …

  • 18 views
  • 03 Mar, 2022
  • 2 locations