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Found 38 clinical trials
Platelet Transfusion in Acute-on Chronic Liver Failure

2-3 grade and inhibition rate beyond 70% was improved and the 28-day mortality decreased after platelet transfusion. Whether platelet transfusion can prolong survival time needs to be determined in

  • 0 views
  • 26 Jan, 2021
  • 8 locations
Platelets or Fibrinogen as First-line Treatment for Bleeding During Pedatric Heart Surgery

The study aims to test whether platelet transfusion or fibrinogen concentrate is the most effective treatment of intraoperative bleeding, when performing open heart surgery with cardiopulmonary

  • 0 views
  • 25 Mar, 2021
  • 1 location
Hyperbaric Oxygen Therapy for Hemorrhagic Cystitis Post HSCT

, immunosuppressant reduction, and platelet transfusion. Patients with viral infection may be treated with antiviral agents, but their efficacy is limited. When the HC was considered to be associated with aGVHD, some

graft versus host disease
hematologic disorders
clot formation
cell transplantation
antiviral agents
  • 1 views
  • 18 Sep, 2021
  • 1 location
Enhancement of the Haemostatic Effect of Platelets in the Presence of High Normal Concentrations of Von Willebrand Factor (Will-Plate)

Assessment of high-normal dosage of Wilate ® compared to placebo administered in combination with platelets to assess reduction of amount of blood loss, need of transfusion products and outcome (length of stay, mortality) in patients with bleeding in comparison.

ticagrelor
hemostatic
coagulation factor
clopidogrel
prasugrel
  • 0 views
  • 06 May, 2022
  • 1 location
Platelet Transfusions in Hematopoietic Stem Cell Transplantation (The PATH Trial) (PATH)

It is hypothesized that a strategy using prophylactic oral and intravenous Tranexamic Acid (TXA) with therapeutic platelet transfusions (if required) is safe and more effective than prophylactic

cell transplantation
tranexamic acid
hematologic malignancy
  • 0 views
  • 22 Mar, 2022
  • 3 locations
TRial to EvaluAte Tranexamic Acid Therapy in Thrombocytopenia

The purpose of this study is to test whether giving tranexamic acid to patients receiving treatment for blood cancers reduces the risk of bleeding or death, and the need for platelet

cancer
cell transplantation
tranexamic acid
hematologic malignancy
  • 704 views
  • 29 Sep, 2021
  • 28 locations
The Cryopreserved vs. Liquid Platelets Trial

This trial is a phase III multicentre blinded randomised controlled clinical non-inferiority trial of cryopreserved platelets vs. conventional liquid-stored platelets for the management of surgical bleeding. The aim of the study is to assess the efficacy, safety and cost effectiveness of cryopreserved platelets, compared to conventional liquid-stored platelets, for the …

  • 0 views
  • 07 Sep, 2021
  • 2 locations
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions (INDEPENDENCE)

The purpose of this Phase 3 study is to evaluate the efficacy and safety of Luspatercept compared with placebo in subjects with myeloproliferative neoplasm (MPN)-associated Myelofibrosis (MF) and anemia on concomitant Janus kinase 2 (JAK2) inhibitor therapy and who require red blood cell count (RBC) transfusions. The study is divided …

bilateral oophorectomy
vasectomy
cancer
anemia
  • 28 views
  • 05 May, 2022
  • 124 locations
The SOLID Platelet Study

can cause severe bleeding. Some people are not helped by platelet transfusions at the standard transfusion rate. This is called platelet transfusion refractoriness (PTR). Researchers want to learn

cancer
platelet transfusion
clot
hematologic malignancy
pulmonary hemorrhage
  • 0 views
  • 13 May, 2022
  • 1 location
Study of Efficacy and Safety of Eltrombopag in Lower-risk MDS Patients With Platelet Transfusion Dependence

This study is designed to evaluate the efficacy and safety of eltrombopag monotherapy in Japanese adult patients with platelet transfusion-dependent lower-risk Myelodysplastic syndromes (LR-MDS

  • 0 views
  • 06 May, 2022
  • 17 locations