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Found 65 clinical trials
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Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-

A Phase , Multicenter, Prospective, Randomized, Open Label, Blinded-endpoint (PROBE) Controlled Trial of Recombinant Human TNK Tissue-type Plasminogen Activator (rhTNK-tPA) for Injection Versus

  • 0 views
  • 05 Aug, 2021
  • 61 locations
None
Efficacy and Safety of Butylphthalide for Acute Ischemic Stroke Patients Receiving Intravenous Thrombolysis or Endovascular Treatment

with the evolution of using iv. recombinant tissue plasminogen activatorrtPA and mechanical thrombectomy in acute ischemic strokeAISpatients, it is still undefined whether combination therapy with dl

  • 4 views
  • 26 Mar, 2021
  • 1 location
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REMOTE Ischemic Perconditioning Among Acute Ischemic Stroke Patients ( REMOTE-CAT)

recombinant tissue plasminogen activator (rt-PA) and/or endovascular treatment. Unfortunately, many patients cannot benefit from these therapies due to contraindications or evolution time. Neuroprotective

stroke
ischemia
plasminogen
infarct
alteplase
  • 1 views
  • 23 Jan, 2021
  • 2 locations
None
TENecteplase in Central Retinal Artery Occlusion Stuy (TenCRAOS)

TENecteplase in Central Retinal Artery Occlusion (TenCRAOS): A Prospective, randomized-controlled, double-dummy, double-blind phase 3 multi-centre trial of TNK 0.25 mg/kg + placebo vs. ASA + placebo (2 arms with 1:1 block randomization). A Prospective, randomized-controlled, double-dummy, double-blind phase 3 multi-centre trial of TNK 0.25 mg/kg + placebo vs. ASA + …

  • 0 views
  • 15 Mar, 2021
  • 25 locations
None
BEnefits of Stroke Treatment Delivered Using a Mobile Stroke Unit

The primary goal of this project is to carry out a trial comparing pre-hospital diagnosis and treatment of patients with stroke symptoms using a Mobile Stroke Unit (MSU) with subsequent transfer to a Comprehensive Stroke Center (CSC) Emergency Department (ED) for further management, to standard pre-hospital triage and transport by …

  • 12 views
  • 25 Jan, 2021
  • 1 location
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adaptatiVe Endovascular Strategy to the CloT MRI in Large Intracranial Vessel Occlusion

In the VECTOR trial, the aim is to analyze, in case of SVS+ occlusions, a first line Embotrap II added to CA combined strategy compare to CA alone strategy. Many practitioners are convinced that a first line strategy with CA alone is easy, safe, rapid and efficient. Maybe, after two, …

  • 0 views
  • 24 Jun, 2021
  • 29 locations
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Optimal Post Tpa-Iv Monitoring in Ischemic Stroke

OPTIMISTmain is an investigator-initiated and conducted, international, multicentre, stepped wedge cluster randomized controlled trial comparing the effects of different intensities of nursing care monitoring for patients with acute ischemic stroke of mild severity and without critical care needs after IV-tPA.

  • 0 views
  • 04 Jul, 2021
  • 26 locations
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Study To antagOnize Plasminogen Activator Inhibitor-1 in Severe COVID-19

This is a single-center, randomized double blind placebo controlled trial to evaluate the efficacy and safety of novel PAI-1 inhibitor (TM5614) for high-risk patients hospitalized with severe COVID-19 at Northwestern Memorial Hospital. The patients will be randomized in a 1:1 ratio to receive standard of care plus TM5614 or standard …

  • 0 views
  • 03 Feb, 2021
  • 1 location
None
The Effectiveness of Early Mobilization for Acute Ischemic Stroke Treated With Rt-PA or IA Thrombectomy

The purpose of the study will to test the hypothesis that combining early out-of-bed mobilization within 72 hours of stroke onset with treated by intravenous recombinant tissue-type plasminogen

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Endovascular Stroke Treatment Only (ESTO) Trial

The specific aims of this study are to: Determine whether the endovascular treatment (mechanical thrombectomy) alone without using intravenous (IV) recombinant tissue plasminogen

  • 0 views
  • 05 Mar, 2021
  • 1 location