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Found 21 clinical trials
Caplacizumab and Immunosuppressive Therapy Without Firstline Therapeutic Plasma Exchange in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura (MAYARI)  

plasma exchange (TPE) with primary endpoint of remission in male and female participants aged 18 to 80 years with immune-mediated thrombotic thrombocytopenic purpura (iTTP). The anticipated

  • 1 views
  • 19 Aug, 2022
Comparison Between Bortezomib and Rituximab Plus Plasmapheresis in AMR

and desensitization protocols, and mainly consisted of steroids, plasma exchange (PE), IVIG and RTX in various modalities. More recently, bortezomib was also proposed.To evaluate the role of a

  • 0 views
  • 24 Mar, 2022
  • 1 location
A Study of Imlifidase in Patients With Guillain-Barré Syndrome

The study participants are patients which have been diagnosed with Guillain-Barré Syndrome (GBS) and are planned to receive treatment with intravenous immunoglobulin (IVIg). IVIg is a standard of care treatment for GBS patients. The patients in this study will be treated with the study medicine imlifidase on day 1, and …

  • 60 views
  • 26 Apr, 2022
  • 9 locations
RescuE pLAsma eXchange in Severe COVID-19

evidence for the development of prothrombotic autoantibodies as an epiphenomenon of "Severe Acute Respiratory Syndrome Coronavirus 2" (SARS-CoV-2) infection. Therapeutic plasma exchange ("TPE") is being

  • 0 views
  • 02 Jan, 2022
  • 4 locations
Therapeutic Plasma Exchange in Adult Patients With Severe Sepsis

. Therapeutic plasma exchange (TPE) involves the separation of plasma from whole blood. The removed plasma is 'exchanged or replaced' with either IV fluids, albumin, blood products or a

  • 0 views
  • 22 Mar, 2022
  • 2 locations
Radiation Therapy, Plasma Exchange, and Immunotherapy (Pembrolizumab or Nivolumab) for the Treatment of Melanoma

This early phase I trial investigates how well radiation therapy, plasma exchange, and pembrolizumab or nivolumab work in treating patients with melanoma. Radiation therapy uses high energy x

pembrolizumab
nivolumab
measurable disease
cancer
tumor cells
  • 0 views
  • 29 May, 2022
  • 1 location
TPE in Septic Patients and Influence on Organ Failure (TPEMOF)

Therapeutic plasma exchange (TPE) should used for patients with septic shock in a controlled, prospective study focusing on the organ functions of the patients.

shock
  • 0 views
  • 23 Feb, 2022
  • 1 location
Immunoadsorption in Anti-GBM Glomerulonephritis.

glomerulonephritis. Established treatment is cyclophosphamide and corticosteroids to suppress anti-GBM production and daily plasma exchange to remove circulating anti-GBM antibodies. The vast majority of patients

  • 4 views
  • 15 Feb, 2022
  • 1 location
Immunotherapy in Autoimmune Encephalitis (PE)

The study is to explore the treatment effects and long-term prognosis (12 months and 24 months after immunotherapy) by comparing the early plasma exchange (PE) combined with medication therapy

  • 0 views
  • 03 Mar, 2022
  • 1 location
Autoantibody Reduction for Acute Exacerbations of Idiopathic Pulmonary Fibrosis (STRIVE-IPF)

in AE-IPF and associated with disease severity. The experimental therapy here (therapeutic plasma exchange plus rituximab plus intravenous immunoglobulin) is mechanistically targeted to

  • 33 views
  • 25 Mar, 2022
  • 6 locations