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Found 37 clinical trials
Comparison of Treatment Outcome of Cabergoline According to Target Prolactin Levels in Patients With Prolactinoma

The aim of this study is to investigate whether inhibition of serum prolactin levels below normal range during cabergoline administration may reduce the recurrence rate after drug withdrawal in patients with prolactinomas.

cabergoline
prolactinoma
prolactin
drug withdrawal
  • 90 views
  • 27 Feb, 2022
  • 1 location
A First in Human Study Using 89Zr-cRGDY Ultrasmall Silica Particle Tracers for Malignant Brain Tumors

The purpose of this study is to test if PET scans using 89Zr-DFO-cRGDY-PEG-Cy5-C' dot particles, can be used to take pictures of brain tumors. The investigators want to understand how the particles are distributed and removed from the body, which may help others be treated in the future. This will …

primary brain tumors
cancer
  • 64 views
  • 04 Oct, 2022
  • 1 location
Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery) (DHAPS)

Hyponatremia is defined as sodium below the normal range of 135-145. Symptomatically, it can cause patients to experience a wide range of symptoms including lethargy, headache, nausea, vomiting and in severe cases coma and even death. The goal of this study is to prospectively compare two approaches to the postoperative …

fluid restriction
hormone secreting
ACTH
prolactin
pituitary adenoma
  • 262 views
  • 20 Apr, 2022
  • 1 location
Hypofractionated Proton Therapy for Benign Intracranial Brain Tumors, the HiPPI Study (HiPPI)

This phase II trial studies how well hypofractionated proton or photon radiation therapy works in treating patients with brain tumors. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells. A shorter duration of radiation treatment may avoid some …

meningioma
tumor cells
pituitary
  • 0 views
  • 04 Jun, 2022
  • 1 location
Postoperative Thrombosis Prevention in Patients With CD

Patients with Cushing disease was randomized to 2 groups. After surgery, the patients were managed with mechanical prevention or mechanical prevention plus anticoagulant drugs(LMWH followed by rivaroxaban), VTE was observed 24h, 5day, 4weeks and 12weeks after surgery.Bleeding events were also recorded.

thrombosis
rivaroxaban
lmwh
postoperative thrombosis
clot
  • 0 views
  • 04 Oct, 2022
  • 4 locations
Long-Term Follow-UP of Survivors of Pediatric Cushing Disease

Background The pituitary gland produces hormones. A tumor in this gland can cause it to produce too much of the hormone cortisol. Too much cortisol in the body causes Cushing disease. This disease causes many problems. Some of these problems might persist after the disease is cured. Objective To find …

free cortisol
stimulation test
pituitary
urinary free cortisol
linkage analysis
  • 104 views
  • 27 Oct, 2022
  • 1 location
Somatostatin Analogues in the Treatment of Relapsing GH Pituitary Adenomas After Surgery

At present there are no recommendations regarding the possibility of discontinuing treatment in cases of recurrent acromegaly with good hormonal control. Discontinuation of treatment is therefore most often decided by the practitioner, on the basis of his experience and knowledge of the patient, the long-term course with somatostatin analogues being …

adenoma
growth hormone
somatostatin
pituitary
  • 0 views
  • 15 Dec, 2021
Peri-operative Dynamics of the Growth Hormone Axis in Subjects With Acromegaly

Acromegaly is a rare disorder characterized by excessive production of growth hormone most often by a pituitary adenoma. A pituitary adenoma is a tumor, almost always benign or non-cancerous

growth hormone
igf1
insulin-like growth factor
somatomedin c
pituitary
  • 73 views
  • 24 Jan, 2022
  • 1 location
Pituitary Adenoma and Serum Lipid

Pituitary adenomas are usually benign monoclonal neoplasms caused by a mixture of pituicyte alterations together with a changed endocrine and paracrine regulatory milieu. Thus, it can cause

  • 0 views
  • 27 May, 2022
  • 1 location
Setting Benchmarks for Transsphenoidal Resection of Pituitary Adenomas

To conduct a retrospective multicenter cohort study to define benchmark values for best achievable outcomes following transsphenoidal resection of pituitary adenomas.

  • 0 views
  • 20 Jul, 2021
  • 1 location