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Found 30 clinical trials
Modulating the GIP System in Patients With Acromegaly Due to a Pituitary Tumor (GA-9)

Modulation of the GIP System in Patients With Acromegaly Due to a Pituitary adenoma

  • 11 views
  • 15 Feb, 2022
  • 1 location
Rec-LH PD and Safety Profile in Hypogonadotropic Hypogonadism Men (RHYTHM)

pituitary adenoma-related mass effect. Patients will be randomized (1:1) according to a permuted- blocks randomization list, to the study group, treated with Luveris (increasing doses at two weekly

  • 0 views
  • 05 Mar, 2022
DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

cholangiocarcinoma
infertility
brain metastases
immunosuppressive therapy
extrahepatic cholangiocarcinoma
  • 6651 views
  • 22 Oct, 2022
  • 752 locations
Endocrine Outcome of Surgery for Pituitary Adenoma

Prospective and randomized compare between microsurgical and endoscopic transsphenoidal MRI assisted resection of pituitary adenomas.

  • 5 views
  • 03 Mar, 2022
  • 1 location
Dopamine Agonist Treatment of Non-functioning Pituitary Adenomas

Due to lack of hormone overproduction in non-functioning pituitary adenomas (NFPAs), only the symptomatic adenomas or large adenomas with proven growth and risk for symptoms in near future will

cabergoline
hypopituitarism
prolactin
dopamine agonists
pituitary disorders
  • 65 views
  • 12 Sep, 2021
  • 3 locations
Nasal Packing Following Endoscopic Endonasal Pituitary Resection

There is considerable controversy about the use of nasal packing following endoscopic endonasal resection of pituitary tumors as a necessary treatment amongst Rhinology-Skull Base Surgeons. The justification for the routine use of nasal packing following pituitary surgery is not clear as this practice is not used for equally extensive sinus …

surgery for pituitary tumors
nasal packing
pituitary disorders
  • 15 views
  • 06 May, 2022
  • 1 location
Semi-sitting Versus Supine Position in Endoscopic Skull Base Surgery (PosESS)

This study is to prospectively compare the standard supine (control group) and the semi-sitting position (head elevation of 30°; intervention group) in endoscopic endonasal pituitary surgery.

  • 0 views
  • 20 Apr, 2022
  • 1 location
Nivolumab and Ipilimumab in People With Aggressive Pituitary Tumors

The purpose of this study is to determine if nivolumab and ipilimumab are effective treatment for people with pituitary tumors have gotten worse after surgery and radiation.

pituitary tumor
investigational drug
temozolomide
nivolumab
measurable disease
  • 4 views
  • 03 Jun, 2022
  • 8 locations
Comparison of Treatment Outcome of Cabergoline According to Target Prolactin Levels in Patients With Prolactinoma

The aim of this study is to investigate whether inhibition of serum prolactin levels below normal range during cabergoline administration may reduce the recurrence rate after drug withdrawal in patients with prolactinomas.

prolactin
prolactinoma
cabergoline
drug withdrawal
  • 90 views
  • 27 Feb, 2022
  • 1 location
A First in Human Study Using 89Zr-cRGDY Ultrasmall Silica Particle Tracers for Malignant Brain Tumors

The purpose of this study is to test if PET scans using 89Zr-DFO-cRGDY-PEG-Cy5-C' dot particles, can be used to take pictures of brain tumors. The investigators want to understand how the particles are distributed and removed from the body, which may help others be treated in the future. This will …

cancer
primary brain tumors
  • 64 views
  • 04 Oct, 2022
  • 1 location