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Found 10 clinical trials
Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Presbyopia

This is a Multicenter, Randomized, Double-Masked Placebo-Controlled, Parallel Group Phase 2 Trial Evaluating the Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of

pilocarpine
  • 0 views
  • 23 May, 2022
  • 1 location
Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adults (VISION-2)

Volunteer participants are evaluated for eligibility during a Screening Visit; those meeting study inclusion/exclusion criteria are scheduled for 2 treatment visits. At each treatment visit, 1 of the 2 study treatments is self-administered to both eyes. Afterwards, efficacy and safety assessments are performed over a 3-hour period.

ophthalmic solution
pilocarpine
Accepts healthy volunteers
subjective refraction
  • 6 views
  • 25 May, 2022
  • 9 locations
Wearing-Off Period of Pharmacological Dilation and Anisocoria

measured again. The third type of eye drop used in this study is 1% pilocarpine. 1 % pilocarpine will briefly constrict the eyes. One drop of 1% pilocarpine will be administered to left eye, and the

Accepts healthy volunteers
  • 0 views
  • 13 May, 2022
  • 1 location
Superior vs Temporal Laser Peripheral Iridotomy in Primary Angle Closure Suspects (PACS)

Basic Study Design: Prospective, randomized, single-center, single-blinded study to compare dysphotopsias and pain recollection immediately 2 weeks, and 3 months after LPI in PACS patients who have a clear indication for bilateral LPI. Our null hypothesis is that there is no difference in dysphotopsia or pain levels by LPI position. …

Accepts healthy volunteers
  • 0 views
  • 15 May, 2022
  • 1 location
Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Dry Eye Disease

This is a Multicenter, Randomized, Double-Masked, Placebo-Controlled, Parallel Group Phase 2 Trial Evaluating the Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of

  • 0 views
  • 24 May, 2022
  • 8 locations
A Novel Argon Laser Iridoplasty for Pigment Dispersion Syndrome

prophylactic measure in practice that is aimed at preventing the progression from mere pigment dispersion to pigment dispersion glaucoma is the long term use of miotic eyedrops e.g. Pilocarpine which comes

gonioscopy
ophthalmic solution
pilocarpine
hypertension
glaucoma surgery
  • 0 views
  • 24 Mar, 2022
  • 1 location
Post-stroke Epilepsy: Primary Prophylaxis Study

> We have previously done researches on the medications that might have potential of anti-epileptogenesis in pilocarpine-induced animal models, supporting the concept of antiepileptogenesis, giving

  • 0 views
  • 08 May, 2021
  • 1 location
Beta-3 Agonist and Anti-muscarinic Agent for Sjogren's Syndrome With Overactive Bladder

Overactive bladder is more prevalent among the Sjogren syndrome's population compare to the general population. Both anti-muscarinic agent and beta-3 agonist are recommended as second line treatment for overactive bladder syndrome. However, theoretically, undesirable effect of the anti-muscarinic agent such as dry mouth and constipation would make it less suitable …

  • 0 views
  • 20 Aug, 2021
  • 1 location
The Sinonasal Cavity as a Reservoir for Upper Airway Bacterial Development

While the maternal-newborn exchange of airway microbiota is well-documented, no studies have examined within-subject relationships among the mouth, sinuses, nasopharynx and lungs and the relative abundance of bacterial taxa at those sites. Recent evidence suggests the oral cavity may serve as a reservoir for pathogens that translocate to non-oral locations; …

sweat test
  • 11 views
  • 19 Apr, 2022
  • 1 location
The Role of Bacterial Toxins in Human Skin Disease

Atopic dermatitis and psoriasis are two skin diseases often associated with bacterial infections and inflammation. Studies indicate that skin cells from these patients may have some changes that make these patients more susceptible to bacterial infections. Inflammatory environment may have an effect on the function of skin cells. The purpose …

atopy
topical corticosteroid
bacterial infection
skin biopsy
Accepts healthy volunteers
  • 269 views
  • 23 Feb, 2022
  • 1 location