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Found 58 clinical trials
Double-Masked Study of Photrex (Rostaporfin) Photodynamic Therapy in the Treatment of Age-Related Macular Degeneration

The purpose of this study is to confirm the efficacy and safety of rostaporfin (PHOTREX) photodynamic therapy (PDT) in the treatment of classic and occult subfoveal choroidal

age-related macular degeneration
photodynamic therapy
angiography
neovascularization
fluorescein angiography
  • 38 views
  • 07 Nov, 2020
  • 1 location
Bevacizumab and Photodynamic Therapy in Neovascular Age Related Macular Degeneration

The purpose of this study is to determine if of combination therapy of intravitreal bevacizumab 4 days after the application of photodynamic therapy could improve the visual outcomes of

age-related macular degeneration
photodynamic therapy
verteporfin
corrected visual acuity
bevacizumab
  • 14 views
  • 07 Nov, 2020
  • 1 location
Photodynamic Therapy for Prevention of Nonmelanoma Skin Cancer in Organ Transplant Recipients

The study will draw patients from the Transplant Dermatology specialty clinic, where the investigators see organ transplant recipients (OTR) for regular screening and serve as a regional referral center for this population. Enrollment will be limited to 20 patients. Inclusion criteria are organ transplant recipients status, active immunosuppression for at …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Vitamin D Supplementation as a Neoadjuvant for Photodynamic Therapy of Actinic Keratoses

This is a prospective clinical trial in which 30 patients will receive a brief (5-day or 14-day) supplementation with 10,000 IU of Vitamin D, prior to receiving aminolevulinic acid (ALA)- blue light PDT for the treatment of actinic keratoses (AKs).

vitamin d supplementation
aminolevulinic acid
photodynamic therapy
vitamin d
  • 0 views
  • 25 Jan, 2021
Safety and Feasibility Study of Methylene Blue Photodynamic Therapy to Sterilize Deep Tissue Abscess Cavities

The objectives of this Phase 1 study are to evaluate the safety and feasibility of methylene-blue-mediated photodynamic therapy (MB-PDT) performed at the time of abscess drainage to treat deep

cavities
drainage
methylene
  • 2 views
  • 11 Apr, 2021
  • 1 location
Aminolevulinic Acid-photodynamic Therapy for Facial Actinic Keratosis Treatment and Prevention

Background Actinic keratoses (AKs) are often treated separately, lesion by lesion. However, in the past years, AKs have been described as a field disease and not limited to single clinically apparent lesions. Treatment should therefore target an area of field change which may treat the subclinical AKs and reduce the …

  • 0 views
  • 22 Jan, 2021
  • 1 location
The Study of Plum-blossom Needling Enhancing Efficacy of Aminolevulinic Acid-photodynamic Therapy for Actinic Keratosis

Background Limited in the depth of absorption and penetration of photosensitizers, ALA-PDT treatment is not strong enough for thickening significantly AK lesions. Pre-study has proved that plum-blossom needling facilitates delivery of topical ALA into the dermis. It could help ALA to diffuse a little more broadly in superficial dermis and …

  • 0 views
  • 23 Jan, 2021
  • 2 locations
Study of Treatment Effects of Combination Therapy of Lucentis Plus Reduced Fluence PDT With Visudyne in Patients With Exudative AMD

The purpose of this study is to determine the benefits, if any, of combination therapy with Lucentis plus reduced fluence photodynamic therapy with Visudyne.

retinal hemorrhage
angiography
geographic atrophy
intraocular pressure
neovascularization
  • 27 views
  • 07 Nov, 2020
  • 1 location
Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz ) and BF-RhodoLED in the Treatment of Superficial Basal Cell Carcinoma (sBCC) With Photodynamic Therapy (PDT).

The aim of this study is to test the safety and efficacy of photodynamic therapy (PDT) with the medication Ameluz performed with the PDT-lamp BF-RhodoLED in comparison to the respective placebo

  • 9 views
  • 03 May, 2021
  • 21 locations
Comparing Intravitreal Aflibercept Monotherapy vs Aflibercept Combined With Reduced Fluence PDT in PCV Treatment

objective is to compare the visual improvement from baseline to month 12, in eyes with PCV treated with Aflibercept monotherapy versus combination of Aflibercept with reduced fluence photodynamic therapy

  • 0 views
  • 10 Jun, 2021
  • 3 locations