Found 381 clinical trials
Open-Label, Multicenter, Ph 3 Study to Evaluate the Efficacy and Tolerability of Intravesical Vicinium™ in Subjects With Non Muscle-Invasive Carcinoma in Situ and/or High-Grade Papillary Disease of the Bladder Treated With BCG. Clinical trial NCT02449239, VB4-845-02-IIIA.
Open-Label, Multicenter, Ph 3 Study to Evaluate the Efficacy and Tolerability of Intravesical Vicinium™ in Subjects With Non Muscle-Invasive Carcinoma in Situ and/or High-Grade Papillary Disease of
- 189 views
- 02 Sep, 2021
- 1 location
Ph 2a study of CY6463 in participants with Alzheimer’s disease and vascular pathology
This study is being conducted to evaluate an oral investigational drug called CY6463 in individuals 60 years of age and older who have Alzheimer’s disease (AD) and common cardiovascular risk factors such as high blood pressure, diabetes, high cholesterol, and/or elevated body mass. The main goals of this study are to …
- 0 views
- 23 Jun, 2022
- 5 locations
A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Oral Treprostinil in Subjects with Pulmonary Hypertension (PH) in Heart Failure with Preserved Ejection Fraction (HFpEF)
A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Oral Treprostinil in Subjects with Pulmonary Hypertension (PH) in Heart Failure with Preserved
- 1004 views
- 25 Mar, 2021
- 1 location
Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease
Background: Some people with the same disorder on a genetic level have more complications than others. Researchers want to look for a link between the PKLR gene and sickle cell disease (SCD) symptoms. The PKLR gene helps create a protein, called pyruvate kinase that is essential in normal functioning of …
- 63 views
- 22 Dec, 2020
- 1 location
Optimization of TKIs Treatment and Quality of Life in Ph+ CML Patients ≥60 Years in Deep Molecular Response
(Tasigna), or Dasatinib (Sprycel) will be given intermittently at the same daily dose that was given daily at the time of the enrollment . Chronic phase Ph+ CML patients in stable major molecular response
- 3 views
- 01 May, 2022
- 1 location
Influence of Manipulation of Oocytes and Embryos in Low Oxygen Tension on Assisted Reproduction Technology Outcome
and pH parameters have been adjusted according to in vivo values in order to improve in-vitro fertilization (IVF) outcomes. Embryos of most mammals, including that of humans, are not exposed to oxygen
- 11 views
- 03 Jun, 2021
- 1 location
Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia
The aim of this study is to support development of asciminib in the pediatric population (1 to <18 years) previously treated with one or more TKIs. Full extrapolation of the efficacy of asciminib from adult to pediatric patients will be conducted. Full extrapolation is based on the concept that CML …
- 0 views
- 27 Jun, 2022
- 19 locations
Speeding the Weaning up: Aggressive Screening Criteria and Higher Minimal Ventilatory Settings.
Hypothesis In patients with less than 4 high risk factors for reintubation excluding body mass index >30 and hypercapnia during the spontaneous breathing trial (SBT) (low and intermediate risk for extubation failure), who receive preventive therapy with high flow nasal cannula (HFNC), the use of SBT with "HIGH minimal ventilator …
- 0 views
- 03 May, 2021
- 1 location
Effect of Flow Rate and pH on Muscle Acidosis
drug application and sng or pain. Also, they try to find if the pH of a solution will affect muscle acidosis.
- 0 views
- 26 Dec, 2021
- 1 location