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Found 381 clinical trials
Featured trial
Open-Label, Multicenter, Ph 3 Study to Evaluate the Efficacy and Tolerability of Intravesical Vicinium™ in Subjects With Non Muscle-Invasive Carcinoma in Situ and/or High-Grade Papillary Disease of the Bladder Treated With BCG. Clinical trial NCT02449239, VB4-845-02-IIIA.

Open-Label, Multicenter, Ph 3 Study to Evaluate the Efficacy and Tolerability of Intravesical Vicinium™ in Subjects With Non Muscle-Invasive Carcinoma in Situ and/or High-Grade Papillary Disease of

neutrophil count
serum bilirubin
cancer
  • 189 views
  • 02 Sep, 2021
  • 1 location
Featured trial
Ph 2a study of CY6463 in participants with Alzheimer’s disease and vascular pathology

This study is being conducted to evaluate an oral investigational drug called CY6463 in individuals 60 years of age and older who have Alzheimer’s disease (AD) and common cardiovascular risk factors such as high blood pressure, diabetes, high cholesterol, and/or elevated body mass. The main goals of this study are to …

dementia
mental state examination
mini-mental state examination
alzheimer's disease
  • 0 views
  • 23 Jun, 2022
  • 5 locations
Featured trial
A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Oral Treprostinil in Subjects with Pulmonary Hypertension (PH) in Heart Failure with Preserved Ejection Fraction (HFpEF)

A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Oral Treprostinil in Subjects with Pulmonary Hypertension (PH) in Heart Failure with Preserved

  • 1004 views
  • 25 Mar, 2021
  • 1 location
Featured trial
Birth Control

Birth Control

  • 3350 views
  • 25 Mar, 2021
  • 1 location
Featured trial
Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease

Background: Some people with the same disorder on a genetic level have more complications than others. Researchers want to look for a link between the PKLR gene and sickle cell disease (SCD) symptoms. The PKLR gene helps create a protein, called pyruvate kinase that is essential in normal functioning of …

red blood cell disorder
sickle cell anemia
sickle cell disease
  • 63 views
  • 22 Dec, 2020
  • 1 location
Optimization of TKIs Treatment and Quality of Life in Ph+ CML Patients ≥60 Years in Deep Molecular Response

(Tasigna), or Dasatinib (Sprycel) will be given intermittently at the same daily dose that was given daily at the time of the enrollment . Chronic phase Ph+ CML patients in stable major molecular response

imatinib
tasigna
gleevec
dasatinib
nilotinib
  • 3 views
  • 01 May, 2022
  • 1 location
Influence of Manipulation of Oocytes and Embryos in Low Oxygen Tension on Assisted Reproduction Technology Outcome

and pH parameters have been adjusted according to in vivo values in order to improve in-vitro fertilization (IVF) outcomes. Embryos of most mammals, including that of humans, are not exposed to oxygen

  • 11 views
  • 03 Jun, 2021
  • 1 location
Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

The aim of this study is to support development of asciminib in the pediatric population (1 to <18 years) previously treated with one or more TKIs. Full extrapolation of the efficacy of asciminib from adult to pediatric patients will be conducted. Full extrapolation is based on the concept that CML …

asciminib
leukemia
basophils
  • 0 views
  • 27 Jun, 2022
  • 19 locations
Speeding the Weaning up: Aggressive Screening Criteria and Higher Minimal Ventilatory Settings.

Hypothesis In patients with less than 4 high risk factors for reintubation excluding body mass index >30 and hypercapnia during the spontaneous breathing trial (SBT) (low and intermediate risk for extubation failure), who receive preventive therapy with high flow nasal cannula (HFNC), the use of SBT with "HIGH minimal ventilator …

  • 0 views
  • 03 May, 2021
  • 1 location
Effect of Flow Rate and pH on Muscle Acidosis

drug application and sng or pain. Also, they try to find if the pH of a solution will affect muscle acidosis.

Accepts healthy volunteers
  • 0 views
  • 26 Dec, 2021
  • 1 location