Found 54 clinical trials
-
Phase 1 trial
-
Accepting Seniors
-
Accepting adults
-
10s of participants
-
An interventional trial
-
For all genders
-
Oncology
-
Currently Recruiting
BN-Brachyury Entinostat Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)
Background Breast cancer is the second most common cause of U.S. cancer deaths in women. Immunotherapy drugs use a person s immune system to fight cancer. Researchers want to see if a new combination of immunotherapy drugs can help treat breast cancer that has gone to places in the body …
- 0 views
- 04 Mar, 2021
- 1 location
-
Accepting Seniors
-
Accepting adults
-
100s of participants
-
An observational study
-
For females only
-
Currently Recruiting
Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer
This study gathers information from the blood cells and tumor tissue during treatment with anti-HER2 therapies, such as trastuzumab, pertuzumab, lapatinib, or neratinib, in patients with HER2
- 0 views
- 25 Jan, 2021
- 1 location
-
Accepting Seniors
-
Accepting adults
-
10s of participants
-
An observational study
-
For all genders
-
Currently Recruiting
A Study to Measure the Expression of the HER2-HER3 Dimer in Tumour and Blood (Exosomes) Samples From Patients With HER2 Positive Breast Cancer Receiving HER2 Targeted Therapies
The treatment of breast cancer is determined by its 'receptor (or signal) status'. Receptors are signals present on all cells and if abnormal can drive cancer growth. One of the signals that can drive breast cancer growth is the HER2 receptor/signal. One quarter of all breast cancers are found to …
- 0 views
- 23 Jan, 2021
- 2 locations
-
Accepting Seniors
-
Accepting adults
-
100s of participants
-
An observational study
-
For all genders
-
Oncology
-
Currently Recruiting
Brain Monitoring for High Risk of Brain Metastases in Metastatic Breast Cancer
In general, brain metastases found after development of neurologic symptoms have poor prognosis. Therefore, the investigators aim to investigate whether regular brain MRI (Magnetic Resonance Imaging) can detect early brain metastases and influence survival through early brain management in HER2-positive and triple negative breast cancer.
- 0 views
- 26 Jan, 2021
- 1 location