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Found 54 clinical trials
BN-Brachyury Entinostat Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)

Background Breast cancer is the second most common cause of U.S. cancer deaths in women. Immunotherapy drugs use a person s immune system to fight cancer. Researchers want to see if a new combination of immunotherapy drugs can help treat breast cancer that has gone to places in the body …

  • 0 views
  • 04 Mar, 2021
  • 1 location
Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer

This study gathers information from the blood cells and tumor tissue during treatment with anti-HER2 therapies, such as trastuzumab, pertuzumab, lapatinib, or neratinib, in patients with HER2

lapatinib
HER2
trastuzumab
estrogen
progesterone receptor
  • 0 views
  • 25 Jan, 2021
  • 1 location
A Study to Measure the Expression of the HER2-HER3 Dimer in Tumour and Blood (Exosomes) Samples From Patients With HER2 Positive Breast Cancer Receiving HER2 Targeted Therapies

The treatment of breast cancer is determined by its 'receptor (or signal) status'. Receptors are signals present on all cells and if abnormal can drive cancer growth. One of the signals that can drive breast cancer growth is the HER2 receptor/signal. One quarter of all breast cancers are found to …

core needle biopsy
HER2
trastuzumab
taxane
fret
  • 0 views
  • 23 Jan, 2021
  • 2 locations
Brain Monitoring for High Risk of Brain Metastases in Metastatic Breast Cancer

In general, brain metastases found after development of neurologic symptoms have poor prognosis. Therefore, the investigators aim to investigate whether regular brain MRI (Magnetic Resonance Imaging) can detect early brain metastases and influence survival through early brain management in HER2-positive and triple negative breast cancer.

brain metastases
HER2
triple negative breast cancer
stage iv breast cancer
cancer
  • 0 views
  • 26 Jan, 2021
  • 1 location