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Found 15 clinical trials
Atrioventricular Junction Ablation and Biventricular Pacing for Atrial Fibrillation and Heart Failure

There is evidence of superiority of AV junction ablation strategy over pharmacological therapy only for symptoms of atrial fibrillation, but not for heart failure, hospitalization, morbidity and mortality. Hypothesis of trial is that AV junction ablation is superior to pharmacological therapy as regard hospitalization and mortality

  • 16 views
  • 02 Feb, 2021
  • 1 location
The Effect of Losartan on Atrial Fibrillation (AF) Burden and Pacemaker Dependence in Patients With Sick Sinus Syndrome

This is a an investigator-initial, multicenter, open-label, randomized, parallel-group comparative study to evaluate the effect on the incidence of AF and pacemaker dependence in SSS patients receiving physiological atrial-based pacing alone or adding losartan 100mg to physiological atrial-based pacing treatment. The duration of the study will be approximately 13 months, …

  • 7 views
  • 07 Nov, 2020
  • 1 location
The Danish Warfarin-Dialysis Study - Safety and Efficacy of Warfarin in Patients With Atrial Fibrillation on Dialysis

The study aims to evaluate the appropriateness of initiating oral anticoagulation for stroke risk reduction in dialysis populations with atrial fibrillation. Specifically, the study will assess the overall safety, tolerability, and efficacy of initiating treatment with Warfarin in patients with end-stage renal disease on dialysis and de novo atrial fibrillation.

  • 0 views
  • 23 Jan, 2021
  • 1 location
Exercise Training in Patients With Persistent or Permanent Atrial Fibrillation

exercise capacity and quality of life in patients with persistent or permanent atrial fibrillation. Positive findings are vitally important for these patients, given the condition's substantial morbidity

fibrillation
permanent atrial fibrillation
  • 12 views
  • 26 Jan, 2021
  • 2 locations
IvaBRAdine blocK of Funny Current for Heart Rate Control in permanEnt Atrial Fibrillation. (BRAKE-AF Study).

The BRAKE-AF Study is a phase III, randomised, controlled, multicentric, open-label clinical trial to prove the noninferiority of ivabradine versus digoxin in the treatment of permanent atrial

beta blockers
fibrillation
atrial fibrillation
calcium channel blockers
antiarrhythmic drug
  • 1 views
  • 23 Jan, 2021
  • 11 locations
Resynchronization/Defibrillation for Ambulatory Heart Failure Trial in Patients With Permanent Atrial Fibrillation

Atrial fibrillation (AF) and heart failure (HF) are two common heart conditions that are encountered with an increase in death and suffering. When both these two conditions occur in a patient, the patient's prognosis is poor with a reduced quality of life and impaired heart function. These patients have enlarged …

dyspnea
fibrillation
edema
atrial fibrillation
medical therapy
  • 77 views
  • 05 Apr, 2021
  • 18 locations
Lenient Rate Control Versus Strict Rate Control for Atrial Fibrillation. The Danish Atrial Fibrillation Randomised Clinical Trial

patients with permanent atrial fibrillation. The investigators will therefore undertake a randomised, superiority trial at four hospitals in Denmark.

  • 0 views
  • 01 Apr, 2021
  • 4 locations
Irbesartan and Adhesion Molecules in AF

Experimental data suggest that angiotensin II-antagonists reduce the atrial expression of prothrombotic adhesion molecules and oxidative stress parameters. The present study is designed to investigate the effects on angiotensin II-antagonist irbesartan to reduce the amounts of circulating oxidative stress markers and adhesion molecules in patients with persistent atrial fibrillation.

persistent atrial fibrillation
angiotensin
  • 10 views
  • 07 Nov, 2020
  • 1 location
Performing a Low-dose Whole-body Angiography as the First Element of an Imaging Assessment Following Stroke / TIA

The main objective of this study is to compare two post-stroke/TIA (transient ischemic attack) imaging strategies in terms of the number of clinically important (i.e. requiring specific treatment according to current recommendations) lesions detected. The first strategy is the current/usual strategy in each participating centre and the second strategy consists …

stroke
ct scan
angiography
transient ischemic attack
  • 0 views
  • 24 Jan, 2021
  • 2 locations
Treatment Success With the CoolLoop Cryoablation System

fibrillation (permanent atrial fibrillation excepted) over a follow-up period of 36 months. A further aim of this study is to evaluate the average duration of procedure and fluoroscopy times.

fibrillation
permanent atrial fibrillation
atrial fibrillation
electrocardiogram
  • 1 views
  • 25 Jan, 2021
  • 3 locations