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Found 50 clinical trials
Feasibility of the LUM Imaging System for Peritoneal Surface Malignancies

This single-site, feasibility study to assess the initial safety and efficacy of the LUM Imaging System for in vivo imaging of metastases to the peritoneum from primary gastrointestinal cancer, ovarian cancer and mesothelioma. This feasibility study consists of two parts: (a) a dose escalation phase to select the optimal dose …

  • 0 views
  • 07 Feb, 2022
  • 1 location
PIPAC in Multimodal Therapy for Patients With Oligometastatic Peritoneal Gastric Cancer (PIPAC_VEROne)

Peritoneal Carcinomatosis is the most frequent site of metastases observed in patients with gastric cancer. Current standard treatment for these patients is palliative systemic chemotherapy, but

  • 0 views
  • 04 Oct, 2022
  • 1 location
Efficacy of HIPEC in Patients With Colorectal Cancer at High Risk of Peritoneal Carcinomatosis

The purpose of this study is to determine the efficacy of adjuvant HIPEC with Mitomycin C after colectomy in the treatment of colorectal cancer patients at high risk of peritoneal carcinomatosis

hyperthermic intraperitoneal chemotherapy
mitomycin
adenocarcinoma
colorectal adenocarcinoma
systemic chemotherapy
  • 15 views
  • 25 Jan, 2021
  • 33 locations
PIPAC With Nab-paclitaxel and Cisplatin in Peritoneal Carcinomatosis

Phase Ib trial including investigating the combination of nab-paclitaxel and cisplatin in patients diagnosed with peritoneal carcinomatosis related to pancreatic, oeso-gastric, ovarian cancer or

  • 2 views
  • 26 Sep, 2021
  • 2 locations
Intraperitoneal Paclitaxel-loaded TPM for Treatment of Peritoneal Carcinomatosis

A first-in-human, unblinded, phase I trial of Paclitaxel-loaded tumor penetrating microparticles (TPM) in peritoneal carcinomatosis patients who are not eligible for standard-of-care therapeutic

  • 0 views
  • 13 Jul, 2022
  • 1 location
Dedicated MR Imaging vs Surgical Staging of Peritoneal Carcinomatosis in Colorectal Cancer (DISCO)

MRI is a potentially powerful tool to reliably determine the intra-abdominal tumor load and relations with intra-abdominal organs. In recent years diffusion weighted MRI has proven its value as a highly sensitive technique to detect small malignant disease in a wide variety of cancers [1-3]. However, literature concerning the clinical …

intraperitoneal chemotherapy
cancer
hyperthermic intraperitoneal chemotherapy
metastasis
peritoneal metastases
  • 3 views
  • 24 Feb, 2022
  • 1 location
Study of Sequential Systemic Therapy + Intraperitoneal Paclitaxel in Gastric/GEJ Peritoneal Carcinomatosis

with cytology positive peritoneal lavage and/or peritoneal carcinomatosis.

  • 0 views
  • 16 Mar, 2021
  • 1 location
Study of Radspherin® in Recurrent Ovarian Cancer Subjects With Peritoneal Carcinomatosis

RAD-18-001 is a First-In-Man, Dose Escalation study conducted at 2 sites. The dose escalation will be performed based on a 3 + 3 design. Increasing dose levels starting at 1 MBq will be followed by 2, 4 and 7 MBq. If the highest dose level of 7 MBq is reached …

cancer
recurrent ovarian cancer
cancer of the ovary
carcinoma
neutrophil count
  • 14 views
  • 07 Oct, 2022
  • 2 locations
  • 0 views
  • 18 Nov, 2021
  • 1 location
Complete Cytoreduction Followed by IP and Systemic Chemotherapies for Gastric Cancer With Peritoneal Carcinomatosis (CRS-IP)

Background: Approximately 15% of gastric adenocarcinoma patients presents with peritoneal carcinomatosis (PC) at the first encounter and is regarded as an unresectable and end-stage disease. The

fluorouracil
adenocarcinoma
cancer chemotherapy
gastric adenocarcinoma
peritoneal carcinomatosis
  • 0 views
  • 21 Mar, 2022
  • 1 location