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Found 451 clinical trials
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

This phase III trial studies how well active surveillance, bleomycin, etoposide, carboplatin or cisplatin work in treating pediatric and adult patients with germ cell tumors. Active surveillance may help doctors to monitor subjects with low risk germ cell tumors after their tumor is removed. Drugs used in chemotherapy, such as …

seminoma
mg++
tumor cells
neutrophil count
beta-human chorionic gonadotropin
  • 596 views
  • 14 Apr, 2022
  • 342 locations
NR in Chemo-induced Peripheral Neuropathy

The purpose of this single-arm phase II trial is to determine whether nicotinamide riboside (NIAGEN) prevents the progression of peripheral sensory neuropathy in patients receiving infusions of paclitaxel or nab-paclitaxel for the treatment of metastatic breast cancer or recurrent platinum-resistant ovarian, endometrial, peritoneal, or fallopian tube cancer.

breast cancer
trastuzumab
bevacizumab
monoclonal antibodies
paclitaxel
  • 77 views
  • 09 Feb, 2022
  • 2 locations
Neuromuscular Electrical Stimulation For The Treatment of Diabetic Peripheral Neuropathy (NMES for DPN)

Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, affecting almost 50% of people with diabetes over the course of their lives. Symptoms vary from numbness to

foot ulceration
diabetes
weakness
burning sensation
nerve conduction studies
  • 44 views
  • 23 Mar, 2022
  • 1 location
Voxx Human Performance Technology Socks for Chemotherapy-Induced Peripheral Neuropathy

This is a double blind, randomized, crossover pilot study of Voxx Human Performance Technology Socks versus placebo socks for the treatment of chemotherapy-induced peripheral neuropathy in

neuralgia
paresthesia
dysesthesias
herceptin
platinum-based chemotherapy
  • 67 views
  • 22 Mar, 2022
  • 1 location
"Prevention of Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer Patients"

The aim of this study is to evaluate the effect of pentoxifylline 400 mg twice daily administration on the prevention of paclitaxel-Induced peripheral neuropathy in breast cancer patients.

paclitaxel
cancer
immunomodulators
  • 0 views
  • 21 Mar, 2022
  • 1 location
  • 0 views
  • 07 Apr, 2022
  • 2 locations
Efficacy of Cilostazol in Prevention of Peripheral Neuropathy

several mechanisms concerning pathophysiology of paclitaxel induced peripheral neuropathy. One of the main mechanisms is induction of Schwann cell dedifferentiation by paclitaxel. These cells are myelin

paclitaxel
cancer
  • 0 views
  • 13 May, 2022
  • 1 location
Ultrasound for the Detection of Oxaliplatin-Induced Peripheral Neuropathy

This pilot clinical trial studies how well ultrasound works in detecting oxaliplatin-induced neuropathy in patients with gastrointestinal cancer. Ultrasound may work better in diagnosing and detecting neuropathy in gastrointestinal cancer patients treated with the chemotherapy drug called a oxaliplatin.

chemotherapy drug
neuropathy
oxaliplatin
cancer
  • 3 views
  • 20 Apr, 2022
  • 1 location
Impact of an Orthotic Intervention in Children With Peripheral Neuropathy (IOPN)

This research study will investigate the effect of two orthotic (brace) devices for the ankle and foot on walking and ankle flexibility in children with cancer not involving the brain or spinal cord.

peripheral neuropathy
spinal cord
cancer
  • 120 views
  • 13 Feb, 2022
  • 2 locations
Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy

This phase II trial studies whether using exercise is better than the usual approach for treating chemotherapy-induced peripheral neuropathy (CIPN). CIPN occurs when chemotherapy damages the

cancer
  • 0 views
  • 23 Mar, 2022
  • 1 location