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Found 458 clinical trials
Efficacy of Gembrax Followed by Folfirinox Versus Folfirinox Alone in First Metastatic Line Pancreatic Cancer Patients (GABRINOX2)

The aim of this study is to evaluate the efficacy of sequential treatment (Gabrinox) comprising Gembrax regimen (Gemcitabine -Abraxane) followed by the Folfirinox regimen (5FU, Oxaliplatin and Irinotecan) compared to folfirinox alone in patients treated in first metastatic line pancreatic cancer

  • 0 views
  • 23 Mar, 2022
  • 1 location
The Role of Postoperative Cycles in the Perioperative Chemotherapy for Gastric Cancer (STOPEROPCHEM)

Taking into account the substantial doubts concerning the potential benefit of postoperative part in the perioperative chemotherapy regimen we designed a study assessing value of this approach in gastric cancer. To improve compliance with a protocol regimen of this aggressive combined therapy we replaced tested in the MAGIC trial ECF …

capecitabine
laparoscopy
endoscopic ultrasound
cancer chemotherapy
oxaliplatin
  • 26 views
  • 22 Jan, 2022
  • 2 locations
Efficacy and Safety of MEDI7352 in Subjects With Painful Diabetic Neuropathy

This is a study investigating the effect of MEDI7352 on chronic pain in patients with painful diabetic neuropathy. The study incudes a screening period of up to 45 days and a 12-week treatment period during which MEDI7352 or placebo will be administered intravenously (IV) on 6 occasions, with each dose …

body mass index
diabetic neuropathy
painful diabetic neuropathy
analgesics
administered intravenously
  • 168 views
  • 21 Jul, 2022
  • 24 locations
A Study to Learn How Safe BAY2395840 is and How Well it Works in Participants Who Have Diabetic Nerve Pain

Researchers are looking for a better way to treat people who have diabetic neuropathic pain (DNP), a condition in which diabetes results in pain due to nerve damage. People with diabetes have high blood sugar levels. Over the time, high blood sugar levels can cause damage to the nerves in …

type 2 diabetes mellitus
sugars
electrocardiogram
antidiabetic agents
  • 0 views
  • 15 Jul, 2022
  • 26 locations
Pediatric Long-Term Follow-up and Rollover Study

A roll-over study to assess long-term effect in pediatric patients treated with dabrafenib and/or trametinib.

dabrafenib
trametinib
  • 487 views
  • 06 May, 2022
  • 16 locations
Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

incidence and/or severity of acute vincristine-induced peripheral neuropathy can be reduced by decreasing the dosage of vincristine in patients with the high-risk CEP72 TT genotype or by shortening the

cytarabine
dasatinib
dexamethasone
etoposide
vorinostat
  • 278 views
  • 11 May, 2022
  • 7 locations
XELOX for 4 Months Versus 6 Months in Gastric Cancer (LOMAC)

Our study aims to compare the efficacy and safety of capecitabine and oxaliplatin for 4 months versus 6 months as adjuvant chemotherapy after D2 Gastrectomy in patients with gastric cancer. Hypothesis: For gastric patients after D2 Gastrectomy, capecitabine and oxaliplatin for 4 months show noninferiority to capecitabine and oxaliplatin for …

adjuvant chemotherapy
adenocarcinoma
immunostimulants
cancer chemotherapy
oxaliplatin
  • 33 views
  • 22 Jan, 2021
  • 10 locations
Optimal Duration of Oxaliplatin in Adjuvant XELOX for Gastric Cancer Patients (EXODOX)

This study aims to compare the efficacy and safety of reduced adjuvant XELOX treatment (4 cycles of XELOX followed by 4 cycles of capecitabine alone) to standard adjuvant XELOX treatment (8 cycles of XELOX).

renal function
oxaliplatin
xelox regimen
capecitabine
adenocarcinoma
  • 0 views
  • 17 Mar, 2022
  • 1 location
Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA

There are two study questions we are asking in this randomized phase II/III trial based on a blood biomarker, Epstein Barr virus (EBV) deoxyribonucleic acid (DNA) for locoregionally advanced non-metastatic nasopharyngeal cancer. All patients will first undergo standard concurrent chemotherapy and radiation therapy. When this standard treatment is completed, if …

  • 410 views
  • 14 May, 2022
  • 114 locations
A Study for the Adjuvant Treatment of Breast Cancer

Studies on postoperative adjuvant albumin paclitaxel in domestic breast cancer patients are less reported, especially in large samples, and more studies focus more on the safety and tolerability of albumin paclitaxel use. Head-to-head studies of white violet and docetaxel are not supported by data at this time, but some studies …

adjuvant chemotherapy
trastuzumab
estrogen
ki-67
docetaxel
  • 0 views
  • 14 Jul, 2022
  • 1 location