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Found 498 clinical trials
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Diabetic Foot Ulcer Recurrence: Pilot Study

In this prospective pilot study, patients with DFU visiting the Indiana University Comprehensive Wound Center will be enrolled. Patients enrolled in the study will be followed for 16 weeks for wound closure(Phase A), and will then begin Phase B where TEWL measurements and wound recurrence will be followed up for …

foot ulcer
diabetic foot
  • 12 views
  • 16 Jul, 2021
  • 1 location
None
Safety and Efficacy of ActiGraft Compared to Standard of Care in DFUs

The study is a multi-center, prospective, randomized, controlled, single blinded clinical study consisting of 150 subjects from up to 20 centers. The subjects are randomized to receive 1 of 2 treatments, either with ActiGraft and standard of care (SOC) or with SOC alone. The target ulcers are evaluated weekly by …

healing ulcer
diabetes
alginate
glycosylated hemoglobin
debridement
  • 77 views
  • 26 Jan, 2021
  • 14 locations
None
A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot

The purpose of this clinical investigation is to assess performance of the Medaxis Debritom+ and to collect subject outcome data in the treatment of diabetic foot ulcers (DFU) vs Standard sharp debridement.

wound dressing
alginate
foot ulcer
osteomyelitis
debridement
  • 0 views
  • 25 Jan, 2021
  • 2 locations
None
Appropriate Strategy of Surgical Treatment in Ischemic Diabetic Foot

This cohort study aims to evaluate the outcomes of appropriate surgical treatment strategies in diabetic foot ulcers with different rate of popliteal artery stenosis(<50% or 50%). In this study, patients with Texas university grade 2-4(stage C-D) ischemic diabetic foot ulcers will be included. Data of patients who underwent surgical treatment …

  • 0 views
  • 27 Jan, 2021
  • 1 location
None
Sealed Therapeutic Shoe as Treatment of Diabetic Foot Ulcers

Total contact casts (TCCs) are effective treatment of plantar diabetic foot ulcers because they effectively offload the ulcer and are non-removable, resulting in high adherence to using the device. However, TCCs are not widely used in clinical practice because they negatively impact gait and daily activities. A new treatment concept …

  • 0 views
  • 23 Jan, 2021
  • 3 locations
None
Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine

The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective laparoscopic gynecological surgery

opioid
analgesia
anesthesia
lidocaine
ketamine
  • 0 views
  • 26 Oct, 2021
  • 1 location
None
Study to Evaluate Automated Intensity Management in Patients Undergoing a BSC SCS Temporary Trial

The purpose of the study is to assess the feasibility of using information extracted from physiologic signals to automatically adjust stimulation in patients undergoing Spinal Cord Stimulation (SCS).

spinal cord
  • 0 views
  • 12 Aug, 2021
  • 1 location
None
The Role of Skin Microecology in Diabetic Skin Lesions

This study is an observational study. Collect cotton swabs of the surface skin are obtained from the non-diabetic and diabetic patients hospitalized in the Nanfang Hospital of Southern Medical University. The investigators use omics technology to identify the structure and functions of cutaneous microbiome, analyze the characteristics of the skin …

osteomyelitis
debridement
diabetes
diabetic foot
  • 0 views
  • 23 Aug, 2021
  • 1 location
None
Post-healing Follow-up Study in People With Remission of a Diabetic Foot Ulcer

To evaluate the benefit of multidisciplinary specific follow-up of patients with a healed diabetic foot ulcer at the rate of two annual consultation on wound recurrence.

diabetes
foot ulcer
diabetic foot
  • 0 views
  • 01 Oct, 2021
  • 1 location
None
Prostacyclin (PGI2) Pathway to Enhance Wound Healing in Diabetic Foot Ulcers

Prospective, monocentric, pathophysiological study, comparing 3 parallel groups: healthy controls; patients with diabetes and without DFU; patients with diabetes and with DFU. To address secondary objectives, samples from a fourth group will be collected.

neuropathy
foot ulcer
skin ulcers
Accepts healthy volunteers
diabetes
  • 0 views
  • 06 Nov, 2021
  • 1 location