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Found 3 clinical trials
Telmisartan vs. Perindopril in Mild-Moderate Alzheimer's Disease Patients (SARTAN-AD)

To conduct a proof of concept study in patients with mild to moderate Alzheimer's Disease in order to determine if there is less global brain atrophy over one year, as measured by ventricular enlargement as a primary outcome measure, when patients are randomized to treatment with an angiotensin receptor blocker …

stroke
cholinesterase inhibitors
cholinesterase
angiotensin
antihypertensive drugs
  • 262 views
  • 15 May, 2022
  • 8 locations
ACES - ACE Inhibitors Combined With Exercise for Seniors With Hypertension (ACES)

The purpose of this project is to conduct a randomized, controlled trial (RCT) to determine if choice of antihypertensive medication influences changes in functional status and other cardiovascular risk factors among older persons with hypertension when combined with physical exercise.

hypertension
hydrochlorothiazide
antihypertensive drugs
systolic blood pressure
aerobic exercise
  • 175 views
  • 24 May, 2022
  • 3 locations
Central Blood Pressure and Variability Evaluation (CAVE-ON)

Background: A sub-study of the AARDVARK (Aortic Aneurysmal Regression of Dilation: Value of ACE-Inhibition on RisK) trial indicated a statistically significant association between central blood pressure (BP) variability and abdominal aortic aneurysm (AAA) growth. The role of anti-hypertensive adherence has not been explored in the context of AAA growth. Objective: …

  • 0 views
  • 04 Oct, 2022
  • 1 location