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Found 46 clinical trials
Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients

Takayasu arteritis (TAK) is a rare chronic inflammatory arteritis, which lacks an effective well-accepted intervention strategy. Here we tried to classify TAK patients in 3 levels, including mild, moderate, and severe, and prescribe methotrexate and tofacitinib randomly in mild and moderate patients, to observe the relatively better treatment strategy, facilitating …

  • 01 Mar, 2022
  • 1 location
Treat COVID-19 Patients With Regadenoson

More than 17 million people have been infected and more than 677K lives have been lost since the COVID-19 pandemic. Unfortunately, there is neither an effective treatment nor is there a vaccination for this deadly virus. The moderate to severe COVID-19 patients suffer acute lung injury and need oxygen therapy, …

respiratory failure
  • 24 Mar, 2022
  • 1 location
Multiparametric MRI for Assessing Radiotherapy Treatment Response of Prostate Cancer (NA_00067284)

Prostate cancer is one of most common cancers in America, affecting 1 in 6 men. External beam radiation therapy is one of the common methods to treat prostate cancer. Although radiotherapy is effective, side effects to the adjacent normal organs limit the therapeutic ratio. Those side effects are usually associated …

external beam radiation therapy
  • 25 Oct, 2022
  • 1 location
Effects of Testosterone Undecanoate vs Placebo on Intrahepatic Fat Content in Overweight/Obese Men With T2DM or Prediabetes and Hypogonadism (Test2Func)

The epidemics of obesity, MeTSy, T2DM and CVD are increasing worldwide. Non-alcoholic fatty liver disease (NAFLD) is becoming recognized as a condition possibly involved in the pathogenesis of these diseases. The prevailing hypothesis for NAFLD pathogenesis is the 'two-hit' model, with insulin resistance and hyperinsulinemia playing essential roles, which have …

  • 02 May, 2022
Brain Glioma Registry Combining Clinical and Imaging Information

This registry aims to collect clinical and radiologic information including detailed clinical, conventional MR and advanced MR imaging data of patients with brain gliomas. Advanced MR imaging may include diffusion-weighted imaging, perfusion-weighted imaging (dynamic susceptibility contrast, arterial spin labeling, dynamic contrast enhancement), and chemical exchange saturation transfer (CEST) imaging. This …

  • 24 Jan, 2021
  • 1 location
Measurement of Brain Perfusion by a MR Perfusion Imaging Called eASL in Children's Cerebral Arteriopathies. (PEACE)

The MR sequence called MR-ASL is used to measure cerebral perfusion in children. This ASL sequence is used with a unique post-labeling delay (PLD) due to the technical impossibility of setting different post-labeling delays. The use of a single post-labeling, chosen by the pediatric radiology department of the Necker hospital, …

  • 04 Oct, 2022
  • 1 location
Myocardial Perfusion Imaging by 15O-H2O PET/CT

The trial will include 2500 patients with evident or suspected ischemic heart disease refered to Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, for perfusion

perfusion imaging
ct scan
  • 15 Nov, 2021
  • 1 location
The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry (SCAD)

> A prospective sub-study of echocardiographic findings after SCAD that includes perfusion imaging (Lumason contrast) is available to patients who are evaluated at Mayo Clinic, Rochester, MN. A

Accepts healthy volunteers
  • 22 Mar, 2022
  • 1 location
Pulmonary Embolism Prognosis Model

The purpose of this study is to analyze the clinical manifestations, imaging features, and prognosis-related factors of pulmonary embolism, and to explore the prognosis risk assessment model for Chinese patients

  • 24 Jan, 2021
  • 1 location
MR Based Prediction of Molecular Pathology in Glioma Using Artificial Intelligence

This registry aims to collect clinical, molecular and radiologic data including detailed clinical parameters, molecular pathology (1p/19q co-deletion, MGMT methylation, IDH and TERTp mutations, etc) and conventional/advanced/new MR sequences (T1, T1c, T2, FLAIR, ADC, DTI, PWI, etc) of patients with primary gliomas. By leveraging artificial intelligence, this registry will seek …

tumor resection
tumour resection
  • 15 Feb, 2021
  • 1 location