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Found 394 clinical trials
Featured trial
Sternal Cerclage (sternal bone closure after open heart surgery)

The purpose of the study is to learn which treatment option is better for patients who have multi-vessel coronary artery disease (blockages in more than one vessel supplying blood to the heart muscle).

acute coronary syndrome
coronary revascularization
  • 05 Feb, 2021
  • 1 location
Intravascular Ultrasound Guidance for Complex High-risk Indicated Procedures (IVUS-CHIP)

The IVUS CHIP trial is a post-marketing strategy study in which patients with complex coronary lesions, undergoing percutaneous coronary intervention (PCI), are treated either with intravascular

  • 04 Oct, 2022
  • 25 locations
The OPTIMAL Randomized Controlled Trial (OPTIMAL)

qualitative angio(QCA)-guided Percutaneous Coronary Intervention (PCI). Patients will be consented prior to the PCI procedure and then followed up to 2 years after the index procedure. Patients will

  • 04 Oct, 2022
  • 23 locations
Ticagrelor De-escalation Strategy in East Asian Patients With AMI

more incidence of bleedings than pro-drug P2Y12 receptor inhibitor during chronic phase for management of acute myocardial infarction (AMI) following percutaneous coronary intervention (PCI). Also

  • 23 Feb, 2021
  • 1 location
Less Bleeding by Omitting Aspirin in Non-ST-segment Elevation Acute Coronary Syndrome Patients (LEGACY)

. Study population: Adult patients presenting with non-ST segment elevation acute coronary syndrome undergoing percutaneous coronary intervention. Intervention: In the intervention group

  • 01 Jul, 2022
  • 2 locations
Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD) (PROTECT-ICD)

revascularisation (PCI or CABG). ICD implantation after 40 days according to current guidelines (LVEF≤30%, or ≤35% with New York Heart Association (NYHA) class II/III symptoms) could be considered, if part of local

  • 15 May, 2022
  • 26 locations
Rivaroxaban Post-Transradial Access for the Prevention of Radial Artery Occlusion (CAPITAL-RAPTOR)

Coronary angiography is performed to evaluate for obstructive coronary artery disease. This is commonly performed via the transfemoral or transradial approach with the latter increasing in frequency. One of the most common complications of transradial access is radial artery occlusion occurring in ~5% of patients which prohibits the use of …

  • 23 Mar, 2022
  • 2 locations
Testing the Value of Novel Strategy and Its Cost Efficacy in Order to Improve the Poor Outcomes in Cardiogenic Shock

Cardiogenic shock (CGS) affects up to 10% of patients suffering acute coronary syndrome. It has a 30 day mortality of 45-50%. No pharmacological nor intervention/device trials have had any impact on this mortality in the last 20 years. The EURO SHOCK Trial (supported by the European Union Horizons 2020 programme) …

  • 12 May, 2021
  • 47 locations
Fentanyl and Crushed Ticagrelor in Percutaneous Coronary Intervention (FACTPCI)

During a percutaneous coronary intervention (PCI), Fentanyl is commonly used for sedation. Ticagrelor is also routinely used as anti-platelet agent during PCI. However, a recent study has

  • 02 Mar, 2022
  • 1 location
Baduanjin Sequential Therapy and Cardiac Function of AMI With Reduced EF After PCI (BST-AMI)

of Baduanjin sequential therapy on cardiac and physical function in patients with AMI and reduced ejection fraction after primary PCI.

  • 22 Mar, 2022
  • 1 location