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Found 262 clinical trials
Featured trial
Sternal Cerclage (sternal bone closure after open heart surgery)

The purpose of the study is to learn which treatment option is better for patients who have multi-vessel coronary artery disease (blockages in more than one vessel supplying blood to the heart muscle).

revascularisation
coronary revascularization
acute coronary syndrome
  • 1647 views
  • 05 Feb, 2021
  • 1 location
  • 0 views
  • 10 May, 2022
  • 12 locations
The OPTIMAL Randomized Controlled Trial

qualitative angio(QCA)-guided Percutaneous Coronary Intervention (PCI). Patients will be consented prior to the PCI procedure and then followed up to 2 years after the index procedure. Patients will

  • 0 views
  • 27 Jan, 2021
  • 30 locations
Ticagrelor De-escalation Strategy in East Asian Patients With AMI

more incidence of bleedings than pro-drug P2Y12 receptor inhibitor during chronic phase for management of acute myocardial infarction (AMI) following percutaneous coronary intervention (PCI). Also

  • 0 views
  • 23 Feb, 2021
  • 1 location
Effects of Statin for Elderly Patients With Atherosclerotic Cardiovascular Disease

High-dose statins can reduce mortality and cardiovascular events in patients with established atherosclerotic cardiovascular disease (ASCVD). Therefore, US and European recommendations recommend that established ASCVD patients (coronary artery disease, cerebrovascular disease, peripheral vascular disease) use high-dose statins to lower LDL cholesterol levels by at least 50%. However, in actual practice, …

rosuvastatin
hmg-coa reductase inhibitors
cardiovascular disease
ezetimibe
LDL Cholesterol
  • 0 views
  • 12 Dec, 2021
  • 2 locations
Rivaroxaban Post-Transradial Access for the Prevention of Radial Artery Occlusion (CAPITAL-RAPTOR)

Coronary angiography is performed to evaluate for obstructive coronary artery disease. This is commonly performed via the transfemoral or transradial approach with the latter increasing in frequency. One of the most common complications of transradial access is radial artery occlusion occurring in ~5% of patients which prohibits the use of …

  • 114 views
  • 23 Mar, 2022
  • 2 locations
Testing the Value of Novel Strategy and Its Cost Efficacy in Order to Improve the Poor Outcomes in Cardiogenic Shock

Cardiogenic shock (CGS) affects up to 10% of patients suffering acute coronary syndrome. It has a 30 day mortality of 45-50%. No pharmacological nor intervention/device trials have had any impact on this mortality in the last 20 years. The EURO SHOCK Trial (supported by the European Union Horizons 2020 programme) …

  • 0 views
  • 12 May, 2021
  • 47 locations
Fentanyl and Crushed Ticagrelor in Percutaneous Coronary Intervention (FACTPCI)

During a percutaneous coronary intervention (PCI), Fentanyl is commonly used for sedation. Ticagrelor is also routinely used as anti-platelet agent during PCI. However, a recent study has

ticagrelor
  • 0 views
  • 02 Mar, 2022
  • 1 location
Adenosine Contrast CorrELations in Evaluating RevAscularizaTION (ACCELERATION)

The purpose of this study is to compare FFR measurements done with adenosine to FFR measurements done with contrast, where the contrast is injected using the ACIST CVi automated contrast injector. The ACCELERATION study will support a safer approach to FFR for patients by potentially reducing toxic drug exposure (adenosine). …

iopamidol
stenosis
adenosine
  • 20 views
  • 06 May, 2022
  • 5 locations
Safety and Efficacy of Bivalirudin During Short-term Intervention of Non-infarction Related Artery After PPCI of STEMI

intervention of non-infarction related artery for acute ST-segment elevation myocardial infarction after emergency percutaneous coronary intervention. NACE, MACE, any type of BARC bleeding, stent

  • 0 views
  • 09 May, 2022
  • 1 location