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Found 385 clinical trials
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Sternal Cerclage (sternal bone closure after open heart surgery)

The purpose of the study is to learn which treatment option is better for patients who have multi-vessel coronary artery disease (blockages in more than one vessel supplying blood to the heart muscle).

revascularisation
coronary revascularization
acute coronary syndrome
  • 1160 views
  • 05 Feb, 2021
  • 1 location
Optical Coherence Tomography Versus Intravascular Ultrasound Guided Percutaneous Coronary Intervention

This study is to establish the primary hypothesis that Optical coherence tomography-guided Percutaneous coronary intervention(OCT-guided PCI) is non-inferior to Intravascular ultrasound-guided

  • 0 views
  • 25 Jan, 2021
  • 3 locations
The OPTIMAL Randomized Controlled Trial

qualitative angio(QCA)-guided Percutaneous Coronary Intervention (PCI). Patients will be consented prior to the PCI procedure and then followed up to 2 years after the index procedure. Patients will

  • 0 views
  • 27 Jan, 2021
  • 30 locations
Ticagrelor De-escalation Strategy in East Asian Patients With AMI

more incidence of bleedings than pro-drug P2Y12 receptor inhibitor during chronic phase for management of acute myocardial infarction (AMI) following percutaneous coronary intervention (PCI). Also

  • 0 views
  • 23 Feb, 2021
  • 1 location
Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD)

revascularisation (PCI or CABG). ICD implantation after 40 days according to current guidelines (LVEF30%, or 35% with New York Heart Association (NYHA) class II/III symptoms) could be considered, if part of local

  • 104 views
  • 23 Jan, 2021
  • 36 locations
Rivaroxaban Post-Transradial Access for the Prevention of Radial Artery Occlusion

Coronary angiography is performed to evaluate for obstructive coronary artery disease. This is commonly performed via the transfemoral or transradial approach with the latter increasing in frequency. One of the most common complications of transradial access is radial artery occlusion occurring in ~5% of patients which prohibits the use of …

  • 11 views
  • 26 Jan, 2021
  • 1 location
China Intensive Lipid Lowering With Statins in Acute Coronary Syndrome

In summary, the CHILLAS study will be the first multicenter study performed in a Chinese population using a patient-level analysis to compare the effects and safety of intensive statin therapy with that of moderate statin therapy. Therefore, it will determine whether "lower is better", that is, whether LDL cholesterol lowering …

atorvastatin
LDL Cholesterol
low density lipoprotein
intravascular ultrasound
cardiac event
  • 0 views
  • 07 Nov, 2020
  • 1 location
Testing the Value of Novel Strategy and Its Cost Efficacy in Order to Improve the Poor Outcomes in Cardiogenic Shock

Cardiogenic shock (CGS) affects up to 10% of patients suffering acute coronary syndrome. It has a 30 day mortality of 45-50%. No pharmacological nor intervention/device trials have had any impact on this mortality in the last 20 years. The EURO SHOCK Trial (supported by the European Union Horizons 2020 programme) …

  • 0 views
  • 12 May, 2021
  • 47 locations
Fentanyl and Crushed Ticagrelor in Percutaneous Coronary Intervention

During a percutaneous coronary intervention (PCI), Fentanyl is commonly used for sedation. Ticagrelor is also routinely used as anti-platelet agent during PCI. However, a recent study has

ticagrelor
  • 0 views
  • 11 Feb, 2021
  • 1 location
Adenosine Contrast CorrELations in Evaluating RevAscularizaTION

osmolality. Evaluate the association between final post-PCI FFR and long-term clinical outcomes. The long-term clinical outcomes will include TVR and composite MACE (death, MI, and TVR) at 30 days

iopamidol
adenosine
stenosis
  • 20 views
  • 17 Jun, 2021
  • 5 locations