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Found 46 clinical trials
Featured trial
The effect of daily intake of two different doses of Bifidobacterium Breve Bif195 on small-intestinal damage induced by Acetlysalicylic Acid- a randomized, double-blind, placebo-controlled, three-armed, parallel group trial in healthy volunteers.

common causes of peptic ulcer bleeding in developed countries and is associated with a significant increased risk of upper gastrointestinal (GI) bleeding and ulcers.  Live bacteria formulated

  • 23 Nov, 2020
  • 1 location
Featured trial
Need a Cardiac Stent?

Need a Cardiac Stent?

  • 08 Nov, 2020
  • 1 location
Vonoprazan-Based Triple Therapy in Comparison With Extended Sequential Therapy

This study aims to compare the efficacy of the current standard first-line anti-helicobacter pylori regimen, extended proton pump inhibitor-based sequential therapy, with that of vonoprazan-based triple therapy, through a randomized controlled trial.

  • 23 May, 2022
  • 1 location
Beta-Lactam Containing Regimen for the Shortening of Buruli Ulcer Disease Therapy

Buruli ulcer (BU) is a skin Neglected Tropical Disease (NTD) that is caused by Mycobacterium ulcerans. It affects skin, soft tissues and bones causing long-term morbidity, stigma and disability. The greatest burden falls on children in sub-Saharan Africa. Treating BU requires 8-weeks with daily rifampicin and clarithromycin, wound care, and …

  • 08 Jan, 2022
  • 3 locations
Over-the-scope Clip Versus Through-the-scope Clip for Endoscopic Hemostasis of High Risk Bleeding Peptic Ulcers

To compare in a multicenter, prospective, randomized, controlled trial the efficacy and safety of OTSC versus TTS clip for first-line hemostasis of high risk bleeding peptic ulcers

  • 03 Feb, 2021
  • 1 location
Comparison of Efficacy of Triple Regimen Based on Clarithromycin VS Metronidazole in Children

All children from 1day to 18years of age, diagnosed with peptic ulcer disease due to H pylori at Pakistan Institute of Medical Sciences, Islamabad, from July 2020 to December 2021 will be

  • 28 Jan, 2021
  • 2 locations
Early Videocapsule Endoscopy for Upper Gastrointestinal Bleeding

The objective of this study is to determine whether early video capsule endoscopy (VCE) immediately after a negative gastroscopy in the setting of suspected upper gastrointestinal bleeding (UGIB) improves patient outcomes as compared to the standard approach which typically involves performing colonoscopy prior to small bowel investigations. We aim to …

  • 11 Nov, 2021
  • 1 location
Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis

This prospective, randomized, double-blind study will compare the effect of oral premedication of ibuprofen and methylprednisolone on the anesthetic efficacy of an Inferior Alveolar Nerve Block (IANB) in adult patients with symptomatic irreversible pulpitis.

Accepts healthy volunteers
  • 28 Feb, 2022
  • 1 location
Aspirin for Prevention of Postsurgical Recurrence and Metastasis in Asian Colorectal Cancer Patients: a Multi-center Randomized Trial

standard adjuvant therapy. Individuals with peptic ulcer, bleeding tendency, or previous or ongoing treatment with aspirin or other anticoagulants will be excluded from this trial. Stratification factors

adjuvant therapy
platelet count
  • 21 Jan, 2021
  • 1 location
Non-warfarin Oral AntiCoagulant Resumption After Gastrointestinal Bleeding in Atrial Fibrillation Patients (NOAC-GAP)

Current clinical society guidelines and statements are non-specific and relatively open-ended regarding the optimal timing to restart non-warfarin oral anticoagulant (NOAC) after gastrointestinal bleeding (GIB) in patients with atrial fibrillation (AF) who require the prophylactic medication for stroke prevention. These patients are at increased risk for devastating future thromboembolic events …

  • 03 Feb, 2022
  • 3 locations