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Found 107 clinical trials
Study of Atezolizumab Combination Carboplatin + Paclitaxel + Bevacizumab in EGRF Mutation or ALK Translocation NSCLC

pemetrexed, cisplatin in approximately 228 TKI(tyrosine kinase inhibitor) pre treated patients with Stage IV non squamous non small cell lung cancer with activating EGFR mutation or ALK translocation.

epidermal growth factor
secondary malignant neoplasm of liver
platelet count
epidermal growth factor receptor
atezolizumab
  • 0 views
  • 08 Jan, 2022
  • 1 location
Gefitinib With or Without Chemotherapy in Brain Metastases From Non-small Cell Lung Cancer

This is a multi-center phase II randomized controlled study to assess the efficacy of Gefitinib alone and Gefitinib combinating with Pemetrexed/platinum on patients with brain metastasis from

secondary malignant neoplasm of liver
neutrophil count
whole-brain radiotherapy
lung cancer
liver metastasis
  • 16 views
  • 13 Mar, 2022
A Study of Atezolizumab Compared With Platinum Doublet Chemotherapy for PD-L1 Highly Expressed, Chemotherapy-Naïve Patients With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer

combination with pemetrexed (non-squamous disease) OR gemcitabine or paclitaxel (squamous disease) in highly PD-L1 expressed, chemotherapy-naïve, EGFR/ALK wild type patients with stage IV non-squamous or

measurable disease
squamous non-small cell lung cancer
carboplatin
lung carcinoma
atezolizumab
  • 0 views
  • 09 Aug, 2022
  • 21 locations
Osimertinib Plus Chemotherapy in Uncommon EGFRm NSCLC. (MINOVA)

plus Pemetrexed Chemotherapy, as First-line Treatment in Recurrent or Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Patients with Uncommon Epidermal Growth Factor Receptor Mutations

measurable disease
hysterectomy
osimertinib
lung cancer
carboplatin
  • 0 views
  • 24 Jul, 2022
Rucaparib and Pembrolizumab for Maintenance Therapy in Stage IV Non-Squamous Non-Small Cell Lung Cancer

patients with stage IV non-squamous non-small cell lung cancer (NSCLC) without progressive disease (PD), as confirmed on CT scans, after induction therapy with carboplatin/pemetrexed/pembrolizumab (CPP

measurable disease
squamous non-small cell lung cancer
anaplastic lymphoma
pembrolizumab
carboplatin
  • 8 views
  • 04 Feb, 2022
  • 3 locations
  • 0 views
  • 10 Mar, 2022
  • 1 location
Study of Safety and Efficacy of Brigatinib Plus Chemotherapy or Brigatinib Only in Advanced ALK-Positive Lung Cancer (MASTERPROTOCOL ALK)

brigatinib monotherapy (Arm A) or brigatinib and carboplatin-pemetrexed therapy (Arm B). An estimated 110 patients (55 in Arm A, 55 in Arm B) will be enrolled at approximately 30 centers. A safety phase will

neutrophil count
lipase
serum bilirubin level
carboplatin
lung carcinoma
  • 0 views
  • 10 Jul, 2022
  • 1 location
Treatment of Malignant Peritoneal Mesothelioma (MESOTIP)

study, patients in the experimental arm will be treated by 4 PIPAC (Cisplatine+Doxorubicine) alternating with 6 cycles of standard intravenous chemotherapy (Cisplatine+Pemetrexed). MESOTIP aim

systemic chemotherapy
pemetrexed
cytoreductive surgery
pressurized intraperitoneal aerosol chemotherapy
peritoneal mesothelioma
  • 129 views
  • 14 Nov, 2021
  • 1 location
A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers

-tumour immune response in patients both as monotherapy and in combination pemetrexed/cisplatin/avelumab (Part B Mesothelioma and NSCLC 1st line), in combination with avelumab (Part B Cutaneous Melanoma

pemetrexed
cancer
  • 2 views
  • 03 Jun, 2022
  • 3 locations
Adjuvant Chemotherapy for High Post-operative Recurrence Risk Stage pI Lung Adenocarcinoma

patients. The purpose of this clinical trial is to determine whether the widely used adjuvant chemotherapy strategy cisplatin/ pemetrexed is more effective than no further treatment for Stage pI lung

  • 0 views
  • 22 Jan, 2021
  • 1 location