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Found 107 clinical trials
Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

This phase II trial tests whether TRC102 (methoxyamine hydrochloride) in combination usual care treatment comprised of pemetrexed, cisplatin, and radiation therapy followed by durvalumab works

  • 0 views
  • 05 Jul, 2022
  • 1 location
A Study of Nivolumab and Chemotherapy Followed by Surgery for Mesothelioma

This study will test whether giving nivolumab in combination with pemetrexed and either cisplatin or carboplatin before surgery is a safe and effective approach to treating resectable

karnofsky performance status
pleurectomy
nivolumab
pemetrexed
neutrophil count
  • 1 views
  • 23 Mar, 2022
  • 7 locations
A Phase II Study of Atezolizumab in Combination With Bevacizumab, Carboplatin or Cisplatin, and Pemetrexed for EGFR-mutant Metastatic Non-small Cell Lung Cancer Patients After Failure of EGFR Tyrosine Kinase Inhibitors.

using Atezolizumab, a PD-L1 inhibitor, in combination with bevacizumab, platinum and pemetrexed to treat patients with EGFR mutated, advanced non-small cell lung cancer (NSCLC) after failure of

  • 0 views
  • 25 Mar, 2022
  • 1 location
Camrelizumab With AC in Patients With Brain Metastases of Driven Gene-negative NSCLC

The primary hypothesis is that camrelizumab in combination with pemetrexed/ carboplatin will present a better efficacy for treatment of first line metastatic non-squamous non-small cell lung

hormone therapy
measurable disease
pd-l1
squamous non-small cell lung cancer
lung cancer
  • 1 views
  • 23 Jan, 2021
  • 1 location
A Phase II Study of Neoadjuvant Sotorasib in Combination With Cisplatin or Carboplatin and Pemetrexed for Surgically Resectable Stage IIA-IIIB Non-Squamous Non-Small Cell Lung Cancer With a KRAS p.G12C Mutation

This is a phase II, single-arm, open-label study evaluating the efficacy, safety and tolerability of neoadjuvant sotorasib in combination with cisplatin (or carboplatin) and pemetrexed

pemetrexed
KRAS
lung cancer
carboplatin
lung carcinoma
  • 0 views
  • 22 Apr, 2022
  • 1 location
A Study Evaluating Platinum-Pemetrexed-Atezolizumab (+/-Bevacizumab) for Patients With Stage IIIB/IV Non-squamous Non-small Cell Lung Cancer With EGFR Mutations ALK Rearrangement or ROS1 Fusion Progressing After Targeted Therapies

The objective of this study is to assess the efficacy of the combination of Platinum (carboplatin or cisplatin), Pemetrexed, Atezolizumab+/- Bevacizumab if eligible, in stage IIIB/IV non

  • 0 views
  • 19 Jun, 2021
  • 30 locations
Study on Savolitinib Combined With Osimertinib in Treatment of Advanced NSCLC With MET Amplification

This study will look at how effective the study drug(Savolitinib combined with Osimertinib) versus Pemetrexed combined with platinum in treatment of patients with locally advanced or metastatic

osimertinib
pemetrexed
EGFR
carboplatin
chemoradiotherapy
  • 0 views
  • 08 Dec, 2021
  • 1 location
Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases

evaluate the efficacy and safety of percutaneous Ommaya capsule injection of autologous bi-dimensional specific T cells in the treatment of glioma and combined with pemetrexed in the treatment of brain

  • 0 views
  • 21 Jul, 2022
  • 1 location
A Study of RGX-104 in Patients With Advanced Solid Malignancies

with nivolumab, ipilimumab, docetaxel, or pembrolizumab plus carboplatin/pemetrexed.

endometrial carcinoma
pd-l1
anticoagulant
epidermal growth factor
platelet count
  • 502 views
  • 10 Aug, 2022
  • 13 locations
Neo-DIANA: Neoadjuvant Treatment for EGFR Mutated Patients

neoadjuvant treatment with Carboplatin Pemetrexed Bevacizumab plus Atezolizumab in patients with non-small cell lung carcinoma locally advanced mutated in EGFR

alimta
bevacizumab
carboplatin
lung carcinoma
atezolizumab
  • 0 views
  • 14 Jun, 2022
  • 17 locations