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Found 748 clinical trials
Adjuvant PD-1 Antibody in Combination With Capecitabine for Patients With ICC at High-Risk of Postoperative Recurrence

The purpose of the study is to observe the effect of PD-1 AntibodyTislelizumab Combined With Capecitabine as Adjuvant Therapy to Prevent the Recurrence in High-risk Patients With Cholangiocarcinoma After Curative Resection.

  • 2 views
  • 04 Oct, 2022
  • 1 location
Nadunolimab in Combination With Gemcitabine Plus Carboplatin in Patients With Advanced Triple Negative Breast Cancer. (TRIFOUR)

Triple negative breast cancer (TNBC) represents approximately 15% of all breast cancers (BC) worldwide. The term triple negative means that tumor growth is not stimulated by the hormones estrogen and progesterone, nor by the HER2 protein, so unlike other types of BC, TNBC, which is an aggressive form of BC, …

progesterone
triple negative breast cancer
estrogen
erbb2
HER2
  • 0 views
  • 16 Mar, 2022
  • 8 locations
Selinexor With Multiple Standard Chemotherapy or Immunotherapy Regimens in Treating Patients With Advanced Malignancies

This phase Ib trial studies the side effects and best dose of selinexor when given together with several different standard chemotherapy or immunotherapy regimens in treating patients with malignancies that have spread to other places in the body and usually cannot be cured or controlled with treatment (advanced). Selinexor may …

measurable disease
olaparib
pemetrexed
selinexor
ovarian carcinoma
  • 14 views
  • 07 Oct, 2022
  • 5 locations
The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy (ROME)

This is a randomized, prospective, multicenter, Proof of Concept, Phase II clinical trial Study. The main objective of the study is to evaluate the efficacy (meant as overall response rate ORR) of TT (targeted Therapy) vs SoC (standard of Care) in patients with progressive disease (recurrent and/or metastatic) of breast …

measurable disease
absolute neutrophil count
renal function
cancer
brigatinib
  • 101 views
  • 17 May, 2022
  • 38 locations
DCE-CT of Thoracic Tumors as an Early Biomarker for Treatment Monitoring in Comparison With Morphologic Criteria

DCE-CT of thoracic tumors as an early biomarker for treatment monitoring in comparison with morphologic criteria. Rationale of the clinical investigation For the evaluation of response to anti-tumoral therapy in thoracic tumors, merely morphologic information is often not sufficient for early response evaluation as dimensions of the oncologic lesions are …

  • 0 views
  • 14 Feb, 2021
  • 1 location
KEYMAKER-U01 Master Study: A Phase 2, Umbrella Study With Rolling Arms of Investigational Agents With Either Pembrolizumab in Combination With Chemotherapy or With Pembrolizumab Alone in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)

This study is referred to as the "umbrella master protocol" for pembrolizumab (MK-3475) in the treatment of non-small cell lung cancer (NSCLC). This pembrolizumab NSCLC umbrella master protocol

targeted therapy
lung carcinoma
platinum doublet
pembrolizumab
stage iv non-small cell lung cancer
  • 14 views
  • 15 Oct, 2022
  • 35 locations
  • 0 views
  • 19 Oct, 2022
  • 21 locations
The Utility of Cell-free DNA Methylation Markers for the Response Prediction of Systemic Treatment for Hepatocellular Carcinoma

treatment for liver cancer in National Taiwan University Hospital include Nexavar, Lenvatinib, Avastin, Tecentriq, Strivarga, Cabometyx, Cyramza, Nivolunab, Pembrolizumab, and Yervoy. Weak and uncooperative

  • 0 views
  • 25 Oct, 2022
  • 1 location
A Study of Lenvatinib in Combination With Pembrolizumab in Korean Patients

The purpose of this study is to collect and evaluate the following information in relation to the safety and the efficacy of Lenvatinib in lenvatinib/pembrolizumab combination therapy in the

combination therapy
pembrolizumab
  • 0 views
  • 29 May, 2022
  • 7 locations
The Prospective Non-randomized Case-control Study From Real-world Lung Cancer Patients

The prospective non-randomized case-control study to elucidate optimal target population of immunotherapy from real-world lung cancer patients

targeted therapy
cancer chemotherapy
lung carcinoma
platinum-based chemotherapy
  • 0 views
  • 15 Aug, 2021
  • 1 location