Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 145 clinical trials
Evaluating the Efficacy of Intranasal Oxytocin on Chronic Pain

. Men and women with chronic nerve, muscle, or pelvic pain will be recruited in Vancouver, Calgary, and St. John's. Each person will be assigned to complete three interventions in a random order. Each

fibromyalgia
chronic pain
pain relieving
pain relief
  • 0 views
  • 07 Oct, 2022
  • 3 locations
Brain Effect of Vagal Nerve Stimulation at Rest and Pain

) and prevented the development of acid-induced oesophageal hyperalgesia. Disturbances in ANS function have been reported not only in IBS patients but also in fibromyalgia and chronic pelvic

Accepts healthy volunteers
  • 250 views
  • 02 Mar, 2022
  • 1 location
The Effectiveness of Parassacral Transcutaneous Stimulation Compared to Tibial Transcutaneous Stimulation, Home Protocol and Behavioral Therapy in the Treatment of Female Hyperative Bladder: Randomized Clinical Trial

outcomes: quality of life, sexual function, quality of sleep, anxiety and depression, muscle function (PERFECT and electromyography), lumbar-pelvic pain (pain intensity) and ultrasound. Participants will

Accepts healthy volunteers
urinary urgency
incontinence
  • 0 views
  • 25 Mar, 2022
  • 2 locations
Comparison Between Home-based Wearable Device and Supervised PFMT on SUI/MUI

on examination (>1cm below the hymen on straining); 3)third and fourth degree perineal tear; 4)suffering diastasis recti abdominis and chronic pelvic pain as the primary problem need treatment; 5

  • 0 views
  • 05 May, 2022
  • 1 location
Impedancemetry in Patients Monitored for Pulmonary Hypertension (HPepic)

Monocentric cohort study, prospective, evaluating the variability of cardiac output measurement by resting and stress impedancemetry as a prognostic factor for Pulmonary Hypertension

  • 1 views
  • 15 Jun, 2022
  • 1 location
Effects of Treprostinil on Right Ventricular Structure and Function in Patients With Pulmonary Arterial Hypertension

In a group of patients with PAH treated with treprostinil, the current study aims to investigate the effect of treatment on RV structure and function; and correlate changes in RV structure and function with: World Health Organisation (WHO) class, Six-minute walk test, Quality of life (QoL), and Pre-specified biomarkers (N-terminal …

right heart catheterization
endothelin
walk tests
endothelin receptor antagonist
treprostinil
  • 9 views
  • 15 Feb, 2022
  • 1 location
THERAPY-HYBRID-BPA Trial

Riociguat could improve the exercise capacity and residual symptoms in patients with chronic thromboembolic pulmonary hypertension (CTEPH) even after normalization of pulmonary arterial pressure by balloon pulmonary angioplasty (BPA). This randomized controlled trial study aimed to clarify whether the improvement of peak cardiac index (CI) during exercise maintains or not …

right heart catheterization
riociguat
  • 2 views
  • 26 Jan, 2021
  • 1 location
Study of Angiogenic Cell Therapy for Progressive Pulmonary Hypertension: Intervention With Repeat Dosing of eNOS-enhanced EPCs (SAPPHIRE)

The SAPPHIRE clinical trial seeks to establish the efficacy and safety of repeated monthly dosing of autologous EPCs transfected with human eNOS (heNOS) in patients with symptomatic severe PAH on available PAH-targeted medical therapy.

right heart catheterization
assisted ventilation
scleroderma
congenital heart defects
left ventricular end-diastolic pressure
  • 11 views
  • 18 May, 2022
  • 6 locations
Blood Markers Predict Effect of Normobaric Hypoxia at Rest and During Exercise in Patients With Pulmonary Hypertension (HEXABM)

To study the effect of acute normobaric hypoxia during exercise in patients with pulmonary hypertension on blood markers (serum markers of iron and red blood cell homeostasis and micro-RNAs known to be associated with PH).

sildenafil
hypoxia
  • 0 views
  • 02 Jun, 2022
  • 1 location
An Open-label, Multi-national, Multi-center, Single-arm, Uncontrolled, Long-term Extension Study of Orally Administered Riociguat in Patients With Symptomatic Pulmonary Arterial Hypertension (PAH) Who Received Riociguat in a Bayer Clinical Trial (RIALTO)

To provide riociguat therapy to eligible patients with PAH originating from Bayer-sponsored trials with BAY63-2521/ Riociguat / Adempas® who are currently or recently treated in these trials until lack of patient benefit as assessed by investigator, or commercial availability and reimbursement.

adempas
pulmonary arterial hypertension
riociguat
  • 2 views
  • 24 Oct, 2022
  • 1 location