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Found 5 clinical trials
Acromegaly Combination Treatment Study

In this study the investigators will evaluate whether combination low dose somatostatin receptor ligand (SRL) and weekly or daily Pegvisomant will attain equivalent control of serum IGF-1 levels

hepatic disease
dopamine agonists
lfts
octreotide
somatostatin
  • 185 views
  • 04 Oct, 2021
  • 1 location
Safety and Efficacy of Pegvisomant in Children With Growth Hormone Excess

work; no medical treatment is approved by FDA. Researchers want to see if the drug pegvisomant can help. Objective To test the role of pegvisomant in children and

igf-i
pituitary tumor
medical therapy
growth hormone
hand x-ray
  • 2 views
  • 24 May, 2022
  • 1 location
Growth Hormone as a Model for Reversible Activation of Adipose Tissue Fibrosis

(Pegvisomant). We will use single-cell technologies, fluorescence-activated cell sorting (FACS), RNA sequencing, and cell culture studies on adipose tissue samples, combined with in vivo assessment of adipose

  • 0 views
  • 10 Sep, 2021
  • 1 location
PegvisOMant and the Immune SystEm (PROMISE)

This is a prospective observational pilot study for the evaluation of pegvisomant (PEG) treatment on immune function and its implication on insulin resistance, metabolic complications and fat

insulin
somatostatin
pegvisomant
insulin resistance
  • 0 views
  • 13 Oct, 2021
  • 1 location
Peri-operative Dynamics of the Growth Hormone Axis in Subjects With Acromegaly

Acromegaly is a rare disorder characterized by excessive production of growth hormone most often by a pituitary adenoma. A pituitary adenoma is a tumor, almost always benign or non-cancerous, that grows on the pituitary, a small gland located at the base of the brain. Treatment of acromegaly usually involves surgery, …

adenoma
somatomedin c
igf1
oral glucose tolerance test
insulin-like growth factor
  • 73 views
  • 24 Jan, 2022
  • 1 location