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Found 19 clinical trials
Study to Evaluate the Efficacy and Safety of Dimethyl Fumarate (Tecfidera) and Peginterferon Beta-1a (Plegridy) for the Treatment of Relapsing-Remitting Multiple Sclerosis in Pediatric Participants

The main objective of the study is to evaluate the efficacy of dimethyl fumarate (Tecfidera) and peginterferon beta-1a (Plegridy), both compared with placebo, in pediatric participants with RRMS

relapsing multiple sclerosis
demyelination
tecfidera
fumarate
  • 6 views
  • 01 Apr, 2021
  • 26 locations
A Study to Evaluate the Safety Tolerability and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis

This study will evaluate the safety, tolerability, and descriptive efficacy of BIIB017 in pediatric participants with relapsing-remitting multiple sclerosis (RRMS) and to assess the pharmacokinetics (PK) of BIIB017 in pediatric participants with RRMS in Part 1. In Part 2, the study will evaluate the long-term safety of BIIB017 and further …

relapsing multiple sclerosis
interferon
magnetic resonance imaging brain
  • 109 views
  • 27 Jul, 2021
  • 72 locations
RIBAJUSTE Clinical Trial Investigating the Efficacy and Safety of Dose Adaptation of Ribavirin

The aim of this study is to compare two therapeutical strategies concerning the combination therapy (peginterferon alfa-2a and ribavirin) in naïve patients with chronic hepatitis C of

fibroscan
peginterferon
liver disease
chronic hepatitis
combination therapy
  • 14 views
  • 07 Nov, 2020
  • 1 location
Phase IV Study to Evaluate the Efficacy/Safety to Extend Treatment and High Dose of Ribavirin in co-Infected Patients

); versus Peginterferón alfa-2a (40 KD) 180 μg/week and Ribavirin (1000-1200 mg/day, according to body weight). To evaluate the impact to extend the treatment with Peginterferon alfa-2a and

blood pregnancy test
HIV Infection
peginterferon
ribavirin
ribonucleic acid
  • 10 views
  • 07 Nov, 2020
  • 38 locations
Study of Sequential GSK3228836 and Peginterferon Treatment in Participants With Chronic Hepatitis B (CHB)

This study is intended to evaluate if 12 or 24 weeks of treatment with GSK3228836 followed by up to 24 weeks of pegylated interferon (PegIFN) can increase the rate of hepatitis B virus surface antigen (HBsAg) loss in participants on stable nucleos(t)ide analogue (NA) therapy, and whether virologic response can …

telbivudine
hepatitis
  • 0 views
  • 24 Jul, 2021
  • 48 locations
Thalidomide Plus Peginterferon and Ribavirin in Patients With Interferon Resistance

response in patients with hepatitis C, genotype 1 with peginterferon + ribavirin resistance. 2. To know the response rate in 12 weeks 3. Describe the tolerance and safety of

interferon
peginterferon
ribavirin
liver disease
chronic hepatitis
  • 6 views
  • 07 Nov, 2020
  • 1 location
Optimized Treatment of Peginterferon Alfa 2a/2b in Treatment Experienced Patients With HBV Related Liver Fibrosis

Compared to nucleoside/nucleotide analogues, peginterferon alfa 2a/2b may has more therapeutic efficacy in hepatitis B surface antigen or e antigen seroconversion and anti-tumor occurrence in

hepatitis b antigen
fibroscan
tenofovir
peginterferon
biopsy of liver
  • 3 views
  • 23 Jan, 2021
  • 1 location
Optimized Treatment of Peginterferon Alfa 2a in Treatment Experienced Patients With HBV Related Liver Fibrosis

Compared to TDF, peginterferon alfa 2a may has more therapeutic efficacy in hepatitis B surface antigen or e antigen seroconversion and anti-tumor occurrence in chronic hepatitis b patients. We

hepatitis b antigen
fibroscan
liver cancer
tenofovir
cancer
  • 3 views
  • 24 Jan, 2021
  • 1 location
Peginterferon Lambda-1a for the Prevention and Treatment of SARS-CoV-2 (COVID-19) Infection

This is a phase 2b prospective, randomized, single-blind, controlled trial of a single subcutaneous injection of peginterferon lambda-1a versus placebo for prevention of SARS-CoV-2 infection in

oximetry
covid-19
capillary oxygen saturation
SARS
coronavirus infection
  • 0 views
  • 25 Jul, 2021
  • 1 location
Optimized Treatment of Peginterferon Alfa 2a/2b in Anti-virus Treatment Naive Patients With HBV Related Liver Fibrosis

Compared to nucleoside/nucleotide analogues, peginterferon alfa 2a/2b may has more therapeutic efficacy in hepatitis B surface antigen or e antigen seroconversion and anti-tumor occurrence in

hepatitis b antigen
fibroscan
tenofovir
peginterferon
biopsy of liver
  • 4 views
  • 23 Jan, 2021
  • 1 location