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Found 23 clinical trials
Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more …

cancer
dexamethasone
cytarabine
lymphoid leukemia
combination chemotherapy
  • 1 views
  • 07 Nov, 2020
  • 5 locations
Anti-PD-1 Antibody Combined With Pegaspargase in the Treatment of Advanced Stage NK/T-cell Lymphoma

This open-label, single arm study will evaluate the efficacy and safety of anti-PD-1 antibody in combination with pegaspargase in treatment of newly diagnosed advanced stage NK/T-cell lymphoma

  • 1 views
  • 23 Jan, 2021
  • 1 location
GPED Regimen for Relapsed/Refractory or Advanced ENKTCL

The purpose of this study is to evaluate the efficacy and safety of gemcitabine, pegaspargase, etoposide, and dexamethasone (GPED) in the treatment of Relapsed/Refractory or advanced NK/T-cell

  • 0 views
  • 24 Jan, 2021
  • 1 location
Avastin+ GemAOD As First-Line Treatment in NK/T Cell Lymphoma

The purpose of this study is to evaluate the efficacy and safety of avastin combined with gemcitabine, oxaliplatin, pegaspargase and dexamethasone(Avastin+ GemAOD) as first-line treatment in

  • 9 views
  • 07 Nov, 2020
  • 1 location
Sintilimab With P-GemOx Regimen for Newly Diagnosed Advanced Extranodal Natural Killer/T-cell Lymphoma Nasal Type

The purpose of this multi-center,single arm,phase clinical trail is to determine the safety and efficacy of Sintilimab with P-GemOx (pegaspargase, gemcitabine and oxaliplatin) regimen for newly

  • 0 views
  • 23 Jan, 2021
  • 1 location
A French Protocol for the Treatment of Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents

death. But indeed the use of ASNase varies between protocols considering the different brands, the dose and the administration modalities. Oncaspar (PEGylated E. coli asparaginase, pegaspargase) was

asparaginase
lymphoid leukemia
pegaspargase
induction therapy
  • 0 views
  • 22 Jan, 2021
  • 28 locations
A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

. Drugs used in chemotherapy, such as vincristine, dexamethasone, prednisone, prednisolone, pegaspargase, methotrexate, cytarabine, mercaptopurine, doxorubicin, cyclophosphamide, and thioguanine, work in

blinatumomab
b-cell acute lymphoblastic leukemia
monoclonal antibodies
cytarabine
lymphoma
  • 84 views
  • 14 Jun, 2021
  • 119 locations
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL Mixed Phenotype Acute Leukemia and B-LLy

, vincristine, and pegaspargase work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial will also

testicular
b-cell acute lymphoblastic leukemia
monoclonal antibodies
cytarabine
lymphoma
  • 42 views
  • 15 Jun, 2021
  • 114 locations
Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

lymphoblastic leukemia (T-ALL) and T-lymphoblastic lymphoma (T-LLy) by optimizing pegaspargase and cyclophosphamide treatment and by the addition of new agents in patients with targetable genomic abnormalities

bortezomib
dasatinib
minimal residual disease
tyrosine
cytarabine
  • 230 views
  • 29 Jan, 2021
  • 7 locations
Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

This randomized phase III trial studies how well imatinib mesylate and combination chemotherapy work in treating patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukemia. Imatinib mesylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, work …

b-cell acute lymphoblastic leukemia
anthracyclines
thioguanine
methotrexate
leucovorin
  • 305 views
  • 14 Jun, 2021
  • 186 locations