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Found 18 clinical trials
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Efficacy and Safety of Eslicarbazepine Acetate as adjunctive Therapy for refractory partial seizures in a double blind, randomized, placebo-controlled, parallel-group multicenter clinical trial

Efficacy and Safety of Eslicarbazepine Acetate as adjunctive Therapy for refractory partial seizures in a double blind, randomized, placebo-controlled, parallel-group multicenter clinical trial

  • 40 views
  • 08 Nov, 2020
  • 1 location
featured
Double blind, randomized, historical control study of the safety and efficacy of Eslicarbazepine Acetate Monotherapy in subjects with partial epilepsy not well controlled by current antiepileptic drugs

Double blind, randomized, historical control study of the safety and efficacy of Eslicarbazepine Acetate Monotherapy in subjects with partial epilepsy not well controlled by current antiepileptic drugs

  • 598 views
  • 08 Nov, 2020
  • 1 location
A Pilot Study: Focused Ultrasound Thalamotomy for the Prevention of Secondary Generalization in Focal Onset Epilepsy

The purpose of this study is to assess the safety and feasibility of Magnetic Resonance Imaging-guided focused ultrasound (MRgFUS) in patients with epilepsy whose medicines are not working well. The ExAblate transcranial system is the name of the device that will be used to create and send ultrasound waves through …

  • 25 views
  • 25 Jan, 2021
  • 1 location
Phenylbutyrate for STXBP1 Encephalopathy

STXBP1 Encephalopathy is a severe disease that can cause seizures and developmental delays in infants and children. It occurs when one copy of the STXBP1 gene has a mutation that causes the gene's protein to not work properly. It is possible that a medication called phenylbutyrate may help the protein …

  • 0 views
  • 01 Jul, 2021
  • 1 location
Emotional Processing and Memory Evaluation in Epilepsy Patients

The purpose of the study is to assess the effects of temporal lobe epilepsy (TLE) on memory and emotional functioning. The study will evaluate the known lateralized neurological dysfunction(Right TLE versus Left TLE) on emotional verbal and visual memory function. Study data will assess the ability of participants with known …

temporal lobe epilepsy
intractable epilepsy
seizure
  • 112 views
  • 07 Nov, 2020
  • 1 location
Effects of Keppra on Thinking Emotions and Balance in Elderly Healthy Volunteers

Epilepsy is a common disorder with an incidence of about 6 per 1000. The incidence progressively increases above age 50. By age 75, the incidence is two to three fold compared with any age group. Unfortunately, older individuals are especially at risk to incur significant side effects to anti-epileptic drugs. …

anti-epileptic drug
keppra
levetiracetam
seizure
antiepileptics
  • 4087 views
  • 07 Nov, 2020
  • 1 location
Randomized Double-blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in POS

This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, adjunctive therapy study in subjects with POS, with optional OLE. The study consists of 4 periods as follows: An 8-week of Screening/Baseline Period, 24-week of Double-blind Treatment Period (including a 18-week Titration Phase and 6-week Maintenance Phase), 52-week of Open-label Extension (OLE) …

  • 0 views
  • 14 May, 2021
  • 12 locations
A Study to Evaluate the Efficacy and Safety of Brivaracetam in Study Participants (>=16 to 80 Years of Age) With Epilepsy

The purpose of the study is to evaluate the efficacy of brivaracetam (BRV) compared to placebo (PBO) as adjunctive treatment in subjects (>=16 to 80 years of age) with partial seizures with

brivaracetam
adjunctive treatment
seizure
antiepileptics
vagus nerve stimulation
  • 840 views
  • 16 Jul, 2021
  • 111 locations
Levetiracetam Versus Carbamazepine in Post-Stroke Late Onset Crisis

The principal purpose of the study is to determine the efficacy and safety of Levetiracetam versus Carbamazepine, intended as the number of patients free from crisis during the whole period of treatment, in patients affected by post stroke late onset crisis.

levetiracetam
carbamazepine
  • 35 views
  • 07 Nov, 2020
  • 1 location
A Study of Levetiracetam as Monotherapy or Adjunctive Treatment of Partial Seizures in Pediatric Epileptic Subjects Ranging From 1 Month to Less Than 4 Years of Age

This is a study to confirm the efficacy of levetiracetam as adjunctive treatment or as monotherapy in pediatric epilepsy subjects aged 1 month to less than 4 years of age with partial seizures

antiepileptic
adjunctive treatment
adjunctive therapy
levetiracetam
epilepsy
  • 82 views
  • 19 Jul, 2021
  • 24 locations