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Found 630 clinical trials
Pacing to Maintain Physiologic Ventricular Activation

Right ventricular pacing causes ventricular dyssynchrony and may be associated with impaired outcome. In the last decade, several approaches for more physiological pacing became available and were implemented in the latest guidelines. However, compared to conventional device implantation, cardiac resynchronization, His bundle pacing and left bundle area pacing remain demanding …

cardiac resynchronization therapy
  • 16 Dec, 2021
  • 1 location
Internal Jugular Vein and Spinal-induced Hypotension

The study aims to assess internal jugular vein ultrasound derived measurements and indices prior to spinal anesthesia in elderly population who fulfills predetermined inclusion criteria and might greatly benefit from an appropriate hemodynamic control during orthopedic surgery. Therefore, it is evaluated the diagnostic performance of these indices in predicting spinal-induced …

  • 23 Apr, 2022
  • 1 location
Myval European Study of Myval THV System Implanted in Patients With Native Severe Aortic Valve Stenosis.

Myval European Study: A retrospective, multicentre, observational study in patients presenting with native severe aortic valve stenosis and treated with Myval Transcatheter Heart Valve System in real-world setting.

  • 02 Feb, 2021
  • 2 locations
Cracking Coma: Towards EEG and MRI Based Precision Medicine After Cardiac Arrest

Rationale: 30-70% of comatose patients admitted to the intensive care unit (ICU) after cardiac arrest never regain consciousness as a result of post anoxic encephalopathy (PAE). Early identification of patients without potential for recovery of brain functioning may prevent inappropriate continuation of medical treatment and improve communication between doctors and …

  • 15 May, 2022
  • 3 locations
Heart Failure Monitoring With Eko Electronic Stethoscopes (CardioMEMS)

This study will enroll heart failure (HF) patients who are under active management with an implanted pulmonary artery pressure sensor (CardioMEMS). Subjects will be provided an electronic stethoscope (the Eko DUO) to take at-home heart sound, lung sound, and ECG recordings in conjunction with regimented CardioMEMS measurements. These two datasets …

heart failure
  • 08 Jun, 2022
  • 1 location
Respiratory Variation of Superior Vena Cava in Transthoracic View as a Fluid Responsiveness Predictor

Fluid evaluation is relevant in critical care. Cardiac ultrasound is the first line of evaluation in hemodynamic characterization of patients in shock, to tailor therapy. Fluid responsiveness predictors allow to better decide when to administer fluids, and transesophagic view of superior vena cava is an effective one. Recently a transthoracic …

  • 05 Jun, 2022
  • 1 location
Early Cardiac Magnetic Resonance Imaging in Suspected Non-ST-Elevation Myocardial Infarction

Background and rationale: Evaluating patients with acute chest pain, elevated high-sensitive cardiac troponin (hs-cTn) levels and non-diagnostic electrocardiogram (ECG), i.e. suspected non-ST elevation myocardial infarction (MI), is a daily challenge. Although contemporary hs-cTn assay-based algorithms have greatly facilitated clinical decision-making, still one-quarter of patients is categorized as 'observe' group and …

  • 10 Oct, 2021
  • 1 location
CCM Italian Registry

The Cardiac Contractility Modulation (CCM) system is a cardiac implantable device indicated for the treatment of patients with symptomatic heart failure with left ventricular systolic dysfunction despite optimal medical and electrical therapy. This system consists of a generator to which two stimulation leads are connected, which are fixed on the …

ace inhibitor
angiotensin converting enzyme
heart disease
beta blockers
  • 03 Mar, 2022
  • 1 location
The Carotid Artery Multi-modality Imaging Prognostic (CAMP) Study

Carotid artery disease is a main cause of ischemic stroke and vascular dementia, and a highly prevalent disease. There is uncertainty about the optimal management of patients with serendipitously or systematically detected asymptomatic carotid artery disease, due to the paucity of information on the predictive features of serious vascular events. …

  • 27 Jan, 2021
  • 1 location
Prognosis Impact of NSVTs After an AMI (TeVeO Study).

Nowadays, Sudden Cardiac Death (SCD) due to malignant arrhythmias is an important cause of death among acute myocardial infarction (AMI) survivors. Preventive strategies with implantable cardioverter-defibrillators (ICD) are the best clinical option for patients, but associated sociosanitary impact in the National Health Systems and the fact that current implant strategy …

  • 02 Mar, 2021
  • 1 location