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Found 632 clinical trials
Precision Medicine in Ischemic Stroke and Atrial Fibrillation

The overall goal of this study is to minimize morbidity due to Atrial Fibrillation (AF). The specific objective is to develop and implement a rational and personalized approach to AF risk

  • 0 views
  • 12 May, 2021
  • 1 location
Randomized Evaluation of Decision Support Interventions for Atrial Fibrillation (RED-AF)

participants with Atrial Fibrillation (AF) at 6 study sites. We hypothesize the combination of the PDA and EDA will be more effective in promoting high-quality SDM and in adoption of and adherence to

  • 0 views
  • 03 Jun, 2022
  • 6 locations
Atrial Sensing Capability for Better Detection of Atrial Fibrillation

This prospective multi-center randomized controlled study aims to compare atrial fibrillation detection and inappropriate therapy according to activation of atrial sensing capability in patients

electrocardiogram
fibrillation
implantable cardioverter-defibrillators
  • 0 views
  • 10 Oct, 2021
  • 28 locations
Aspirin Discontinuation After Left Atrial Appendage Occlusion in Atrial Fibrillation (ASPIRIN-LAAO)

appendage occlusion (LAAO). Patients diagnosed with atrial fibrillation and have undergone LAAO will be enrolled in this study. Randomization will be performed at 6 months post-implant. The

clot
acute coronary syndrome
fibrillation
embolism
vascular disease
  • 14 views
  • 09 Feb, 2022
  • 1 location
PREvention of STroke in Intracerebral haemorrhaGE Survivors With Atrial Fibrillation (PRESTIGE-AF)

Atrial fibrillation (AF) is the most common form of irregular heart rhythm. In people with AF, blood clots often form in the heart, which can travel to the brain. Blockage of brain arteries by

brain imaging
clot
fibrillation
warfarin
rivaroxaban
  • 16 views
  • 11 Feb, 2022
  • 16 locations
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG (PACES)

antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying POAF event

clopidogrel
rivaroxaban
dabigatran
antiplatelet therapy
anticoagulants
  • 112 views
  • 27 Apr, 2022
  • 43 locations
EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF) (ENRICH-AF)

ischemic, hemorrhagic and unspecified stroke) in high-risk atrial fibrillation (CHA2DS2-VASc 2) patients with previous intracranial hemorrhage.

vascular disease
fibrillation
atrial fibrillation
anticoagulants
stroke
  • 15 views
  • 16 Feb, 2022
  • 139 locations
Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy (CLOSURE-AF)

The study goal is to determine the clinical benefit of percutaneous catheter-based left atrial appendage (LAA) closure in patients with non-valvular atrial fibrillation (NVAF) at high risk of

fibrillation
warfarin
noac
rivaroxaban
dabigatran
  • 13 views
  • 28 Feb, 2022
  • 17 locations
Reversal of Atrial Substrate to Prevent Atrial (RASTA AF)

A multi-center, randomized trial to examine the effect of aggressive risk factor control and arrhythmia trigger-based intervention on recurrence of atrial fibrillation.

transient ischemic attack
fibrillation
catheter ablation
hypertension
a 12
  • 25 views
  • 02 Mar, 2022
  • 1 location
Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in AF (BRAIN-AF)

This is a prospective, multicenter, randomized, double-blinded clinical trial exploring the efficacy and safety of rivaroxaban as compared to standard of care in reducing stroke, transient ischemic attack (TIA) and neurocognitive decline, in subjects with non-valvular AF and with low risk of stroke.

electrocardiogram
transient ischemic attack
fibrillation
hypertension
diabetes
  • 8 views
  • 22 Jan, 2022
  • 1 location