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Found 512 clinical trials
Open-label Trial in Parkinson's Disease (PD) (TEMPO-4)

The purpose of this study is to evaluate the safety and efficacy of long-term administration of flexible doses of tavapadon in participants with Parkinson's Disease.

carbidopa
amantadine
bradykinesia
levodopa
  • 0 views
  • 14 Jun, 2022
  • 61 locations
A Study in Parkinson's Disease in Patients With Moderate to Severe Dyskinesia (ASTORIA)

The current study will explore the efficacy, safety and tolerability of 2 dose combinations of JM-010 to determine the optimal doses of each component to be studied in confirmatory clinical trials.

combinations
levodopa
dyskinesia
parkinson's disease
  • 10 views
  • 02 May, 2022
  • 4 locations
COMPuter-assisted Self-training to Improve EXecutive Function (COMPEX)

This project explores the effects of specialized computer-based cognitive rehabilitation (CBCR) targeting executive functions in three groups of patients: Stroke, Cardiac Arrest and Parkinson's Disease. The effect of specialized CBCR is compared generally cognitively stimulating activities on a computer

cognitive rehabilitation
rehabilitation program
stroke
cognitive stimulation
  • 0 views
  • 25 Jan, 2022
  • 2 locations
18F-DOPA II - PET Imaging Optimization

A single centre non-randomized, non-blinded phase III prospective cohort study of 18F-DOPA PET/CT imaging in specific patient populations: Pediatric patients (less than 18 years old) with congenital hyperinsulinism. Pediatric patients (less than 18 years old) with neuroblastoma. Pediatric (less than 18 years old) or Adult patients (18 or older) with …

dementia
dopa
parkinson's disease
  • 8 views
  • 03 May, 2022
  • 1 location
Evaluation of Impaired Mobility in Chronic Illness Constitution of a Cohort (EVALMOB)

Chronic illness is a public health issue and mobility loss is frequent in this population. Among its' multiple physical and psychological consequences, increased mortality and cardiovascular morbidity seem the main concern. Therefore, the exploration of locomotor deficiencies, physical capacities and metabolism of patients with chronic illnesses constitutes a major challenge …

chronic disease
  • 0 views
  • 25 Jan, 2022
  • 1 location
The Swedish BioFINDER 2 Study (BioFINDER2)

The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g. to characterize the role of beta-amyloid pathology in early diagnosis of Alzheimer's disease (AD) using amyloid-PET (18F-Flutemetamol) and A analysis in …

cancer
neurodegenerative diseases
vascular disease
neurodegenerative disorders
neurodegenerative disorder
  • 178 views
  • 25 Feb, 2022
  • 1 location
OCTA in Mild Cognitive Impairment and Alzheimer's Disease

This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography angiography (OCTA) to assess the structure and function of the retinal microvasculature in persons with mild cognitive impairment (MCI) and Alzheimer's Disease (AD), Parkinson's Disease (PD) or other neurodegenerative disease, multiple sclerosis, and Huntington's disease.

optical coherence tomography
disease or disorder
neurodegenerative diseases
mild cognitive impairment
huntington's disease
  • 31 views
  • 25 Jan, 2022
  • 1 location
Recovering Damaged Cells for Sequelae Caused by COVID-19 SARS-CoV-2

Post-acute sequelae of SARS-CoV-2 infection can cause multiple system function disorders, and complicated symptoms last for an extended period. The virus can cause this continued infection, or the virus causes immune system function disorder and post-infectious autoimmune disease. The clinical symptoms can be smell loss, taste loss to liver function …

  • 25 views
  • 02 Jun, 2021
  • 1 location
Rural Dementia Caregiver Project

These caregivers are a vulnerable group due to their physical isolation and well-documented rural disparities in health care access and quality. Many rural dementia caregivers experience serious health consequences due to caregiving responsibilities that can limit their ability to maintain their caregiving role. Thus, there is a pressing need for …

depressive symptoms
depressed mood
dementia
depression
Accepts healthy volunteers
  • 0 views
  • 26 Jan, 2022
  • 1 location
Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)

This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.

medical marijuana
disease or disorder
covid-19
Accepts healthy volunteers
brimonidine tartrate ophthalmic solution
  • 15111 views
  • 13 Jun, 2022
  • 16 locations